Q. No.
The vaccine safety testing has been hitherto carried out on
1. Armadillos
2. Monkeys
3. Reindeer
4. Koalas
Match the columns -
|
|
Column-I |
|
Column-II |
|
(A) |
Rosie |
(i) |
a-1 antitrypsin |
|
(B) |
ELISA |
(ii) |
Protein enriched milk |
|
(C) |
ROP |
(iii) |
Test to detect antigen or antibody |
|
(D) |
Emphysema |
(iv) |
Codes for protein involved in plasmid replication |
1. A-ii, B-iii, C-iv, D-i
2. A-i, B-iii, C-iv, D-ii
3. A-ii, B-iii, C-i, D-iv
4. A-iv, B-iii, C-ii, D-i
Which protein has been produced generating a transgenic sheep that is used for replacement therapy for individuals at risk from emphysema?
| 1. | Plasminogen activator (rPA) |
| 2. | α-antitrypsin (ATT) |
| 3. | Casein |
| 4. | Amyloid precursor proteins |
Which of the following statement is incorrect?
| 1. | Golden rice in vitamin A |
| 2. | Human protein obtained from transgenic animals is used to treat emphysema |
| 3. | Human protein-enriched milk, which contained the human alpha-lactalbumin was produced by the transgenic cow, Molly |
| 4. | TPA (Tissue Plasminogen Activator) is used by doctors to dissolve clots after a heart attack in patients |
To test the safety of polio vaccine, the organisms used are transgenic :
1. Mice
2. Pigs
3. Monkey
4. Cattle
Which of the following is correct?
| 1. | The procedure for chemical safety testing / toxicity is the same as that used for testing toxicity of drugs |
| 2. | Transgenic animals are more sensitive to the toxic substances than non-transgenic animals |
| 3. | Golden rice, a genetically engineered rice has high vitamin A (β-carotene) content |
| 4. | All are correct |
Match the following
Column I Column II
(A) -1 antitrypsin (i) SCID
(B) C-peptide (ii) Emphysema
(C) Human lactalbumin (iii) Rosie
(D) ADA deficiency (iv) Proinsulin
A B C D
1. (i) (ii) (iii) (iv)
2. (ii) (iv) (i) (iii)
3. (iii) (iv) (ii) (i)
4. (ii) (iv) (iii) (i)
Genetic engineering has been successfully used for producing
(1) transgenic mice for testing safety of polio vaccine before use in humans
(2) transgenic models for studying new treatments for certain cardiac diseases
(3) Transgenic cow-Rosie which produces high fat milk for making ghee
(4) animals like bulls for farm work as they have super power
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