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Q. No.
With regard to insulin choose the incorrect statement(s).
a. C-peptide is found attached with both A and B chains of insulin with the help of disulphide bonds.
b. In 1983, both A and B chains were produced by introducing alien genes in plasmid of same E.coli by Eli Lilly.
c. A-peptide and B-peptide of insulin are interconnected by peptide bonds in mature insulin.
d. Insulin from an animal source may cause allergy or other types of reactions in some diabetic patients.
Choose the correct answer from the options given below.
1. (a) and (b) only
2. (c) and (d)
3. (a), (b) and (c)
4. (d) only
Subtopic:  Med Applications & Humulin |
 59%
Level 3: 35%-60%
Hints
Assertion (A): Insulin used for diabetes was earlier extracted from the pancreas of slaughtered cattle and pigs but now it is not used.
Reason (R): Aarti along with some other patients took insulin injections in which insulin was from an animal source and they manifested an allergic response to that.
In light of the above statements, select the correct option:
1. Both (A) and (R) are True and (R) is the correct explanation of (A).
2. Both (A) and (R) are True but (R) is not the correct explanation of (A).
3. (A) is True but (R) is False.
4. (A) is False but (R) is True.
Subtopic:  Med Applications & Humulin |
 81%
Level 1: 80%+
Hints
Assertion (A): In 1983, Eli Lilly used E.coli, as heterologous host for the production of humulin 
Reason (R): Production of insulin in E.coli by genetic engineering is possible because bacterial cells can carry out the RNA splicing mechanism 
Choose the correct answer from the options given below 
1. Both (A) and (R) are true and (R) is the correct explanation of the (A) 
2. Both (A) and (R) are true but (R) is not the correct explanation of the (A) 
3. (A) is true but (R) us false 
4. (A) is false but (R) is true 
Subtopic:  Med Applications & Humulin |
 57%
Level 3: 35%-60%
Hints
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Mutations in the CFTR gene cause cystic fibrosis (CF). The non-mutated allele of the gene can be obtained and then introduced into the lung cells of a person with CF using liposomes as a vector. This treatment gives only short-term relief from the symptoms of CF.
Which of the following statements would be a correct explanation of this treatment?
(i) Genes are unstable and break down over time in the cell.
(ii) Lung cells are constantly being replaced and new cells will have the faulty allele.
(iii) The non-mutated allele is recessive.

1. (i) and (ii) only
2. (i) only
3. (ii) only
4. (i) and (iii) only
Subtopic:  Med Applications & Humulin |
 54%
Level 3: 35%-60%

Sorry!! currently, the explanation for the question is not provided. If you need further help, please email at support@neetprep.com with subject: Explanation Missing for Question Id: 345324

Hints

With regard to insulin, choose the correct options:

(a) C-peptide is not present in mature insulin.
(b) The insulin produced by rDNA technology has C-peptide.
(c) The pro-insulin has C-peptide.
(d) A-peptide and B-peptide of insulin are interconnected by disulphide bridges.
Choose the correct answer from the options given below:
1. (a), (c) and (d) only 2. (a) and (d) Only
3. (b) and (d) only 4. (b) and (c) only
Subtopic:  Med Applications & Humulin |
 85%
Level 1: 80%+
NEET - 2021
Hints
Assertion(A): Batch fermentation is said to be closed system.
Reason(R): In batch fermentation, the conditions set up are not changed from outside one fermentation starts.

1. Both (A) and (R) are True and (R) is the correct explanation of (A).
2. Both (A) and (R) are True but (R) is not the correct explanation of (A).
3. (A) is True but (R) is False.
4. Both (A) and (R) are False.
Subtopic:  Med Applications & Humulin |
 71%
Level 2: 60%+
Hints
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Assertion(A): Removal of C-chain results in the maturation of insulin to proinsulin.
Reason(R): Insulin is now-a-days obtained from pig's blood.
 
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Subtopic:  Med Applications & Humulin |
 69%
Level 2: 60%+
Hints
Assertion(A): 'Hirudin' can be extracted from transgenic Brassica napus.
Reason(R): Hirudin is a naturally occurring peptide in the salivary glands of medicinal leeches that has a blood anticoagulant property.
 
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Subtopic:  Med Applications & Humulin |
 54%
Level 3: 35%-60%
Hints
Assertion(A): The recombinant DNA technology have made immense impact in the area of healthcare by enabling mass production of safe and more effective therapeutic drugs.
Reason(R): The recombinant therapeutics do not induce unwanted immunological responses as is common in case of similar products  isolated from non-human sources.
 
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Subtopic:  Med Applications & Humulin | Vaccines |
Level 3: 35%-60%
Hints
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Assertion(A): At present, about 30 recombinant therapeutics have been approved for human use world-wide.
Reason(R): In India, 12 of these are presently being marketed.

1. Both (A) and (R) are True and (R) is the correct explanation of (A).
2. Both (A) and (R) are True but (R) is not the correct explanation of (A).
3. (A) is True but (R) is False.
4. Both (A) and (R) are False.
Subtopic:  Med Applications & Humulin |
 88%
Level 1: 80%+
Hints
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