Match each item in Column I with one item in Column II and chose your answer from the codes given below:

    Column I                   Column II
  (antibiotic)                    (effect)
I. Tetracycline            1. inhibits binding of aminoacyl tRNA to the ribosome
II. Streptomycin        2. inhibits initiation of translation
III. Chloramphenicol  3. inhibits peptidyl transferase
IV. Erythromycin       4. inhibits translocation of mRNA along with ribosome

Codes:

1. 1 2 3 4

2. 2 1 4 3

3. 2 1 3 4

4. 1 2 4 3

The association of histone H₁ with a nucleosome indicates 

(1) transcription is occuring

(2) DNA replication is occuring

(3) the DNA is condensed into chromatin fibre

(4) the DNA double helix is exposed

The equivalent of a structural gene is

(1) muton

(2) cistron

(3) operon

(4) recon

A molecule that can act as a genetic material must fulfill the traits given below, except

(1) it should be able to express itself in the form of 'Mendelian characters'

(2) it should be able to generate its replica

(3) it should be unstable structurally and chemically

(4) it should provide the scope for slow changes that are required for evolution

DNA-dependent RNA polymerase catalyses transcription on one strand of the DNA which is called the 

(1) template strand

(2) coding strand

(3) alpha strand

(4) anti strand

Which one of the following is not applicable to RNA ?

1. Complementary base pairing

2. 5' phosphoryl and 3' hydroxyl ends

3. Heterocyclic nitrogenous bases

4. Chargaff's rule

Commonly used vectors for human genome sequencing are

(1) T-DNA

(2) BAC and YAC

(3) Expression vectors

(4) T/A cloning vectors

The diagram shows an important concept in the genetic implication of DNA. Fill in the blanks A to C

(1) A-transcription, B-replication, C-James Watson

(2) A-translation, B-transcription, C-Ervin Chargaff

(3) A-transcription, B-translation, C-Francis Crick

(4) A-translation, B-extension, C-Rosalind Franklin

If one strand of DNA has the nitrogenous base sequence as ATCTG, what would be the complementary RNA strand sequence?

(1) TTAGU

(2) UAGAC

(3) AACTG

(4) ATCGU

What are those structures that appear as ‘beads-on-string’ in the chromosomes when viewed under electron microscope?

(1) Nucleotides

(2) Nucleosomes

(3) Base pairs

(4) Genes