The length of the DNA molecule greatly exceeds the dimensions of the nucleus in eukaryotic cells. How is this DNA accommodated?

1. Deletion of non-essential genes

2. Super-coiling in nucleosomes

3. DNAse digestion

4. Through the elimination of repetitive DNA

During transcription, RNA polymerase holoenzyme binds to a gene promoter and assumes a saddle-like structure. What is its DNA-binding sequence?

Differentiation of organs and tissues in a developing organism is associated with:

1. developmental mutations

2. differential expression of genes

3. lethal mutations

4. deletion of a gene

The Okazaki fragments in DNA chain growth:

The two polynucleotide chains in DNA are:

1. parallel

2. discontinuous

3. antiparallel

4. semiconservative

One gene-one enzyme relationship was established for the first time in:

1. Neurosporacrassa

2. Salmonella typhimurium

3. Escherichia coli

4. Diplococcuspneumonia

A sequential expression of a set of human genes occurs when a steroid molecule binds to the:

1. transfer RNA

2. messenger RNA

3. DNA sequence

4. ribosome

Which antibiotic inhibits the interaction between t-RNA and m-RNA using bacterial protein synthesis?

1. Erythromycin

2. Neomycin

3. Streptomycin

4. Tetracycline

Amino acid sequence, in protein synthesis is decided by the sequence of:

1. t-RNA

2. m-RNA

3. c-DNA

4. r-RNA

One gene – one enzyme hypothesis was postulated by:

1. R. Franklin

2. Hershey and Chase

3. A. Garrod

4. Beadle and Tatum