Sickle cell anaemia is:

1. an autosomal linked dominant trait
2. caused by substitution of valine by glutamic acid
in the globin chain of haemoglobin
3. caused by a change in base pair of DNA
4. characterized by elongated sickle like RBCs with
a nucleus

Subtopic:  Mendelian Disorders: Sickle Cell Anemia |
 53%
From NCERT
AIPMT - 2009
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NEET 2026 - Target Batch - Vital
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Sickle cell anaemia has not been eliminated from the African population because:

1. It is controlled by recessive genes

2. It is not a fatal disease

3. It provides immunity against malaria

4. It is controlled by dominant genes

Subtopic:  Mendelian Disorders: Sickle Cell Anemia |
 57%
AIPMT - 2006
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Both sickle cell anaemia and Huntington’s chorea are:

1. bacteria-related diseases.

2. congenital disorders

3. pollutant-induced disorders

4. virus-related diseases

Subtopic:  Mendelian Disorders: Sickle Cell Anemia | Mendelian Disorders |
 77%
AIPMT - 2006

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