Assertion: | Although hormones are circulated by blood they act only on their target tissues. |
Reason: | Hormones produce their effects on target tissues by binding to specific proteins called hormone receptors located in the target tissues only. |
1. | Hormones bind to receptors on the cell surface and directly enter the cell to alter DNA transcription. |
2. | Hormones bind to receptors on the cell surface, initiating a signaling cascade that affects cell function. |
3. | Hormones act as enzymes to directly speed up cellular reactions. |
4. | Hormones are transported to the nucleus where they dissolve the nuclear membrane. |
I: | is caused by excessive secretion of adrenal cortex hormones. |
II: | is characterised by altered carbohydrate metabolism causing acute weakness and fatigue. |
Assertion (A): | PTH is a hypocalcaemic hormone. |
Reason (R): | PTH stimulates reabsorption of Ca2+ by the renal tubules. |
1. | Both (A) and (R) are True and (R) correctly explains the (A). |
2. | Both (A) and (R) are True but (R) does not correctly explain the (A). |
3. | (A) is True but (R) is False. |
4. | (A) is False and (R) is True. |
I: | is located dorsal to aorta. |
II: | regresses in size with age. |
Assertion(A): |
Dr. Sharma prescribed Kapil sir (travelling to Berkeley on study leave) Melatonin to overcome jet lag associated with travel across several time zones.
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Reason(R): | Melatonin is secreted by pineal gland. |
1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
3. | (A) is True but (R) is False. |
4. | (A) is False and (R) is True. |
Assertion(A): | Secretion of cortisol by adrenal cortex leads to elevated blood glucose levels. |
Reason(R): | Cortisol causes gluconeogenesis. |
1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
3. | (A) is True but (R) is False. |
4. | (A) is False and (R) is True. |
Column A | Column B | ||
1. | Acromegaly | A. | Deficiency of vasopressin (ADH) |
2. | Cushing's disease | B. | Excess secretion of growth hormone |
3. | Diabetes mellitus | C. | Insulin deficiency or resistance |
4. | Diabetes insipidus | D. | Excess cortisol production |
Assertion (A): | The hypothalamus controls the pituitary gland. |
Reason (R): | The hypothalamus secretes hormones that stimulate or inhibit the release of pituitary hormones. |
1. | Both (A) and (R) are True and (R) is the correct explanation of (A) |
2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
3. | (A) is True but (R) is False. |
4. | Both (A) and (R) are False. |