With regard to mature mRNA in eukaryotes:
1. exons and introns do not appear in the mature RNA
2. exons appear but introns do not appear in the mature RNA
3. introns appear but exons do not appear in the mature RNA
4. both exons and introns appear in the mature RNA
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Subtopic: Transcription |
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The human chromosome with the highest and least number of genes in them are respectively:
1. Chromosome 21 and Y
2. Chromosome 1 and X
3. Chromosome 1 and Y
4. Chromosome X and Y
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Subtopic: Human Genome Project |
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Who amongst the following scientists had no contribution in the development of the double helix model for the structure of DNA?
1. Rosalind Franklin
2. Maurice Wilkins
3. Erwin Chargaff
4. Meselson and Stahl
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Subtopic: DNA Double Helix |
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DNA is a polymer of nucleotides which are linked to each other by 3’-5’ phosphodiester bond. To prevent polymerisation of nucleotides, which of the following modifications would you choose?
1. Replace purine with pyrimidines
2. Remove/Replace 3' OH group in deoxy ribose
3. Remove/Replace 2' OH group with some other group in deoxy ribose
4. Both ‘b’ and ‘c’
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Subtopic: DNA Double Helix |
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Discontinuous synthesis of DNA occurs in one strand, because:
1. DNA molecule being synthesised is very long
2. DNA dependent DNA polymerase catalyses polymerisation only in one direction (5’ → 3’)
3. it is a more efficient process
4. DNA ligase joins the short stretches of DNA
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Subtopic: DNA Replication |
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Which of the following statements is correct about the role of regulatory proteins in transcription in prokaryotes?
1. They only increase expression
2. They only decrease expression
3. They interact with RNA polymerase but do not affect the expression
4. They can act both as activators and as repressors
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Subtopic: Gene Regulation: Introduction |
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