Match the following:
(a) | Inhibitor of catalytic activity of succinate dehydrogenase | (i) | Ricin |
(b) | Possess peptide bonds | (ii) | Malonate |
(c) | Cell wall material in fungi | (iii) | Chitin |
(d) | Secondary metabolite | (iv) | Collagen |
(a) | (b) | (c) | (d) | |
1. | (iii) | (i) | (iv) | (ii) |
2. | (iii) | (iv) | (i) | (ii) |
3. | (ii) | (iii) | (i) | (iv) |
4. | (ii) | (iv) | (iii) | (i) |
Statement I: | Low temperature preserves the enzyme in a temporarily inactive state whereas high temperature destroys enzymatic activity because proteins are denatured by heat. |
Statement II: | When the inhibitor closely resembles the substrate in its molecular structure and inhibits the activity of the enzyme, it is known as competitive inhibitor. |
Assertion (A): | Competitive enzyme inhibition can be overcome by increasing the substrate concentration. |
Reason (R): | Competitive inhibitors bind to a different site on the enzyme, not active site. |
1. | Both (A) and (R) are True and (R) is the correct explanation of (A) |
2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
3. | (A) is True but (R) is False. |
4. | (A) is False but (R) is True. |