In eukaryotes, RNA polymerase I transcribes all the following except:
1. 28S rRNA 2. 8S rRNA
3. 5.8S rRNA 4. 5S rRNA

Subtopic:  Transcription: I |
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Identify the correctly matched pairs:
Scientist Contribution in deciphering genetic code
I: Hargobind Khorana Developed chemical method for synthesising RNA molecules with
defined combinations of bases.
II: Marshall Nirenberg Created cell-free system to facilitate study.
1. Only I
2. Only II
3. Both I and II
4. Neither I nor II
Subtopic:  Genetic Code |
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There is only a single mRNA codon for tryptophan, that is
1. UAC 2. UGG
3. UUU 4. UAG
Subtopic:  Genetic Code |
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All three major cellular RNAs are needed to synthesise a protein in a cell where:
I: mRNA provides the template
II: tRNA brings amino acids and reads the genetic code
III: rRNAs play structural and catalytic role during translation
1. Only I is correct
2. Only I and III are correct
3. Only II and III are correct
4. I, II and III are correct
Subtopic:  Transcription |
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A gene:
I: is defined as the functional unit of inheritance.
II: can also be defined as DNA sequences coding for tRNA or rRNA.
III: can also be defined as certain regulatory sequences.

1. Only I and II are correct
2. Only I and III are correct
3. Only II and III are correct
4. I, II and III are correct
Subtopic:  Gene Regulation: Introduction |
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Consider the given two statements:
Assertion (A): From the very beginning of the proposition of code, it was clear to Francis Crick that there has to be a mechanism to read the code and also to link it to the amino acids.
Reason (R): The tRNA is the adapter molecule.
 
1. Both (A) and (R) are True but (R) does not correctly explain (A).
2. (A) is True but (R) is False.
3. (A) is False but (R) is True.
4. Both (A) and (R) are True and (R) correctly explains (A).   
Subtopic:  Transcription |
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Consider the given two statements:
Assertion (A): The order and sequence of amino acids in a polypeptide are defined by the sequence of bases in the mRNA.
Reason (R): The mRNA is formed in a template independent manner in eukaryotes.
 
1. Both (A) and (R) are True but (R) does not correctly explain (A).
2. (A) is True but (R) is False.
3. (A) is False but (R) is True.
4. Both (A) and (R) are True and (R) correctly explains (A).   
Subtopic:  Translation |
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How many of the given statements regarding ribosomes are correct?
I: Ribosomes are the cellular factory responsible for synthesising proteins.
II: The ribosome consists of structural RNAs and about 800 different proteins.
III: In its inactive state, it exists as two subunits; a large subunit and a small subunit.
IV: When the small subunit encounters an mRNA, the process of translation of the mRNA to protein begins.
1. 1
2. 2
3. 3
4. 4
Subtopic:  Translation |
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In the presence of an inducer, such as lactose or allolactose:
1. the repressor of lac operon is activated allowing RNA polymerase access to the promoter
and transcription proceeds.
2. the repressor of lac operon is inactivated preventing RNA polymerase access to the promoter
and transcription stops.
3. the repressor of lac operon is inactivated allowing RNA polymerase access to the promoter
and transcription proceeds.
4. the repressor of lac operon is activated allowing RNA polymerase access to the promoter
and transcription stops.
Subtopic:  Gene Regulation: Lac Operon |
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In an operon:
1. a polycistronic structural gene is regulated by a common promoter and regulatory genes.
2. the regulation in gene expression is always negative and inducible.
3. the number of structural genes in eukaryotes is much higher than the number of genes in
prokaryotic operon.
4. the role of RNA polymerase is actually performed by accessory proteins like activators
and repressors
Subtopic:  Gene Regulation: Lac Operon |
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