1. | Providing the best catalyst in the form of improved organism usually a microbe or pure enzyme. |
2. | Creating optimal conditions through engineering for a catalyst to act. |
3. | Downstream processing technologies to purify the protein/organic compound. |
4. | Development of new genetically modified microbes that can be used as bio-weapons. |
Consider the two statements:
I: | Retroviruses are useful as vectors in gene therapy. |
II: | They can produce useful gene products in significantly greater quantities than a single human cell can. |
1. Both I and II are correct and II explains I.
2. Both I and II are correct but II does not explain I.
3. Only I is correct.
4. Both I and II are incorrect.
1. | have had their DNA manipulated to possess and express an extra [foreign] gene. |
2. | are genetically modified with the use of foreign genes from a sexually compatible donor organism. |
3. | are produced by interspecific hybridisation. |
4. | are produced by inbreeding. |
Transgenic animals used to test the safety of polio vaccine are:
1. | Mice | 2. | Monkeys |
3. | Rabbits | 4. | Pigs |
The transgenic cow, Rosie, produced milk that:
1. | contained human beta-lactalbumin |
2. | contained interferons to treat viral infections |
3. | contained Alpha-1 – 1 antitrypsin |
4. | is protein enriched |
Alpha-1-antitrypsin was produced in a transgenic sheep, Tracy. This enzyme is used in the treatment of:
1. | Emphysema | 2. | Rheumatoid arthritis |
3. | Ovarian cancer | 4. | Pancreatitis |
At present transgenic animals cannot be used for:
1. | Harvesting biological products |
2. | Testing vaccine safety |
3. | Study of human diseases |
4. | Xenotransplantation |
Transgenic mice are being used to test the safety of polio vaccine. They could replace the use of:
1. | Monkeys | 2. | Rabbits |
3. | Fowl | 4. | Frogs |
Assertion (A): | Transgenic animals can be specifically designed to allow the study of how genes are regulated, and how they affect the normal functions of the body and its development, e.g., study of complex factors involved in growth such as insulin-like growth factor. |
Reason (R): | By introducing genes from other species that alter the formation of this factor and studying the biological effects that result, information is obtained about the biological role of the factor in the body. |
1. | Both (A) and (R) are True and (R) is the correct explanation of (A) |
2. | Both (A) and (R) are True but (R) is not the correct explanation of (A) |
3. | (A) is True but (R) is False |
4. | Both (A) and (R) are False |