Q. No.The genetic material for the first life on the earth was probably:
1. ds DNA 2. ss DNA 3. Protein 4. RNA
What catalyzes the peptide bond formation in prokaryotes?
1. Proteases
2. A ribozyme
3. Sigma subunit of RNA polymerase
4. Rho factor proteins
Identify the correct statements regarding salient features of the Double-helix structure of DNA:
| I: | Backbone is constituted by nitrogenous bases. |
| II: | The two chains have anti-parallel polarity. |
| III. | There is complementary base pairing between nitrogenous bases. |
| IV. | The two chains are coiled in a left-handed fashion. |
| V. | The plane of one base pair stacks over the other. |
| 1. | All except I | 2. | All except I and IV |
| 3. | Only II and III | 4. | Only III |
DNA-dependent DNA polymerases do not:
| 1. | synthesize RNA to prime DNA synthesis |
| 2. | have exonuclease activity |
| 3. | possess proofreading capabilities |
| 4. | synthesize DNA in a 5' to 3' direction |
Transfer of electrophoresis-separated DNA fragments to a filter membrane and subsequent fragment detection by probe hybridization is called as:
| 1. | DNA profiling | 2. | PCR |
| 3. | Southern blotting | 4. | Elution |
In the human genome, the chromosomes with the most and the fewest genes located on them respectively are:
| 1. | 1 and Y | 2. | X and Y |
| 3. | 21 and X | 4. | 11 and Y |
The salient features of the human genome include all of the following except:
| 1. | The functions are unknown for over 50 % of the discovered genes. |
| 2. | More than 2 % of the genome codes for proteins. |
| 3. | Chromosome 1 has the most genes. |
| 4. | Repeated sequences make up a very large portion of the human genome. |
The size of VNTR [used in DNA fingerprinting] varies from:
| 1. | 0.1 to 20 kb | 2. | 20 to 30 kb |
| 3. | 50 to 100 kb | 4. | 115 to 215 kb |
Griffith's experiment discovered bacterial transformation which in his experiment means:
| 1. | A mutation in the R strain made them virulent. |
| 2. | A mutation in the S strain made them non-virulent. |
| 3. | A rough strain passed genetic information to a smooth strain. |
| 4. | A smooth strain passed genetic information to a rough strain. |
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