The backbone of a polynucleotide chain is made of:

1. Sugar and nitrogenous bases
2. Phosphate and nitrogenous bases
3. Sugar and phosphate
4. Sugar, phosphate, and nitrogenous bases

Subtopic:  The DNA | DNA Double Helix |
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Deoxythymidine is:
1. a substituted pyrimidine found only in DNA
2. a nucleoside monophosphate found only in DNA
3. a nucleoside found in DNA
4. a nucleotide formed by chemical modifications in a RNA nucleotide
Subtopic:  DNA Double Helix |
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What would not be true for the structure of a polynucleotide chain?
 
1. 5’-end of polynucleotide chain has a free phosphate moiety at 5'-end of sugar.
2. 3’-end of polynucleotide chain has a free OH group 3'-C of sugar.
3. The backbone of a polynucleotide chain is formed due to sugar and phosphates.
4. The nitrogenous bases linked to phosphate moiety project from the backbone.
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DNA was first identified by:

1.Friedrich Meischer2.Phoebus Levene
3.Linus Pauling4.Erwin Chargaff

Subtopic:  DNA Double Helix |
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In 1953, James Watson and Francis Crick, proposed a very simple but famous Double Helix model for the structure of DNA, based on the X-ray diffraction data produced by:
1. Maurice Wilkins and Rosalind Franklin
2. Beadle and Tatum
3. Temin and Baltimore
4. Avery–MacLeod–McCarty
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According to Erwin Chargaff, in a double-stranded DNA

1. The ratios between Adenine and Thymine, and, Guanine and Cytosine are constant and equal.
2. The ratios between Adenine and Thymine, and, Guanine and Cytosine are constant but are not equal to one.
3. The ratios between Adenine and Guanine, and, Thymine and Cytosine are constant and equal.
4. The ratios between Adenine and Guanine, and, Thymine and Cytosine are constant but are not equal to one.

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“For a double stranded DNA, the ratios between Adenine and Thymine and Guanine and Cytosine are constant and equals one” – this statement is known as:
1. Central dogma of molecular biology
2. Chargaff’s rule
3. Tetra-nucelotide hypothesis by Levene
4. Genetic equilibrium
Subtopic:  DNA Double Helix |
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The base pairing in a double stranded DNA is correctly described as:

1. Similar 2. Identical
3. Complementary 4. Synergistic

Subtopic:  DNA Double Helix |
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If each strand of a dsDNA acts as a template for a new strand, the two daughter DNAs will be:

1. Complementary to each other
2. Identical to the parental DNA
3. Similar to each other
4. Complementary to the parental DNA

Subtopic:  DNA Double Helix |
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Which of the following is not a feature of the double helix model of DNA?

1. The two chains have anti-parallel polarity
2. A purine always comes opposite to a pyrimidine
3. The pitch of the DNA is 3.4 nm
4. The two chains are coiled in a left handed fashion

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