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Match the following:
| (a) | Inhibitor of catalytic activity of succinate dehydrogenase | (i) | Ricin |
| (b) | Possess peptide bonds | (ii) | Malonate |
| (c) | Cell wall material in fungi | (iii) | Chitin |
| (d) | Secondary metabolite | (iv) | Collagen |
Choose the correct option from the following:
| (a) | (b) | (c) | (d) | |
| 1. | (iii) | (i) | (iv) | (ii) |
| 2. | (iii) | (iv) | (i) | (ii) |
| 3. | (ii) | (iii) | (i) | (iv) |
| 4. | (ii) | (iv) | (iii) | (i) |
Subtopic: Â Proteins |Â Enzyme Inhibition |Â Primary & Secondary Metabolites |Â Carbohydrates: Cellulose, Chitin, Inulin & Agar |
 89%
Level 1: 80%+
NEET - 2020
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Consider the given two statements:
| I: | In competitive enzyme inhibition, the substrate and inhibitor cannot bind to the enzyme at the same time. |
| II: | The inhibitor always has a much higher affinity for the active site than the normal substrate. |
| 1. | Both I and II are correct and II explains I |
| 2. | Both I and II are correct but II does not explain I |
| 3. | I is correct but II is incorrect |
| 4. | I is incorrect but II is correct |
Subtopic: Â Enzyme Inhibition |
Level 3: 35%-60%
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Reverse transcriptase is mainly found in retroviruses such as HIV. Four nucleotides are needed for the reaction catalysed by this enzyme.
A group of molecules may inhibit this enzyme. These molecules are structurally similar to the nucleotides but slightly altered so that bonds normally formed in the reaction cannot be made.
Which of the following statements may be correct?
1. The four inhibitor molecules will resemble adenine, thymine, guanine and cytosine.
2. The inhibitor molecules can prevent the formation of phosphodiester bonds.
3. The inhibitor molecules can result in a reduction in the number of new virus particles produced.
1. 1 and 3 only
2. 1, 2 and 3
3. 3 only
4. 1 and 2 only
A group of molecules may inhibit this enzyme. These molecules are structurally similar to the nucleotides but slightly altered so that bonds normally formed in the reaction cannot be made.
Which of the following statements may be correct?
1. The four inhibitor molecules will resemble adenine, thymine, guanine and cytosine.
2. The inhibitor molecules can prevent the formation of phosphodiester bonds.
3. The inhibitor molecules can result in a reduction in the number of new virus particles produced.
1. 1 and 3 only
2. 1, 2 and 3
3. 3 only
4. 1 and 2 only
Subtopic: Â Enzyme Inhibition |
 61%
Level 2: 60%+
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Which of the following statements is/are correct for all enzyme inhibitors?
1. (iv) only
2. (iii) only
3. (i), (ii) and (iii) only
4. (i), (ii) and (iv) only
| (i) | They alter the shape of the active site. |
| (ii) | They denature the enzyme. |
| (iii) | They increase the activation energy of the reaction. |
| (iv) | They reduce the rate of the enzyme catalysed reaction. |
2. (iii) only
3. (i), (ii) and (iii) only
4. (i), (ii) and (iv) only
Subtopic: Â Enzyme Inhibition |
 53%
Level 3: 35%-60%
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Read the statements given below carefully
Out of the four statements given above regarding competitive inhibition, correct one is/are :
1. One
2. Two
3. Three
4. Four
| (a) | The inhibitor closely resembles the enzyme in its molecular structure. |
| (b) | Inhibitor competes with the substrate for substrate binding site of the enzyme. |
| (c) | It leads to decline in activity of the enzyme. |
| (d) | Malonate inhibition by succinate dehydrogenase is an example of the same. |
Out of the four statements given above regarding competitive inhibition, correct one is/are :
1. One
2. Two
3. Three
4. Four
Subtopic: Â Enzyme Inhibition |
Level 4: Below 35%
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| Assertion (A): | An example of non-competitive inhibitor is cyanide. |
| Reason (R): | Cyanide kills animals by inhibiting cytochrome oxidase. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 3. | (A) is true but (R) is false. |
| 4. | Both (A) and (R) are false. |
Subtopic: Â Enzyme Inhibition: Introduction |Â Enzyme Inhibition |Â Properties of Enzymes |
Level 3: 35%-60%
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Which of the following is true for non-competitive enzyme inhibition?
| 1. | Vmax decreases, Km remains same |
| 2. | Inhibitor can attach with the enzyme at a region other than active site |
| 3. | A typical example is cyanide inhibiting cytochrome oxidase |
| 4. | More than one option is true. |
Subtopic: Â Enzyme Inhibition: Introduction |Â Enzyme Inhibition |
 70%
Level 2: 60%+
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Which one of the following is incorrect for uncompetitive inhibition?
| 1. | Vmax and Km both decreases |
| 2. | ES, ESI are possible but EI is not possible |
| 3. | Vmax and Km both increases |
| 4. | All are incorrect |
Subtopic: Â Enzyme Inhibition: Introduction |Â Enzyme Inhibition |
Level 4: Below 35%
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Given below are two statements:
In the light of the above statements, choose the correct answer from the options given below:
1. Statement I is false but Statement II is true.
2. Both Statement I and Statement II are true.
3. Both Statement I and Statement II are false.
4. Statement I is true but Statement II is false.
| Statement I: | Low temperature preserves the enzyme in a temporarily inactive state whereas high temperature destroys enzymatic activity because proteins are denatured by heat. |
| Statement II: | When the inhibitor closely resembles the substrate in its molecular structure and inhibits the activity of the enzyme, it is known as competitive inhibitor. |
1. Statement I is false but Statement II is true.
2. Both Statement I and Statement II are true.
3. Both Statement I and Statement II are false.
4. Statement I is true but Statement II is false.
Subtopic: Â Factors Affecting Enzyme Catalysis Reaction |Â Enzyme Inhibition |
 88%
Level 1: 80%+
NEET - 2023
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