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Q. No.| Assertion (A): | The newly formed mRNA has the same sequence as the coding stand of transcriptional unit with uracil present in place of thymine. |
| Reason (R): | The rule of complementarily guides the formation of DNA and RNA. |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are True and (R) is not the correct explanation of (A). |
| 3. | (A) is True but (R) is False. |
| 4. | (A) is False but (R) is True. |
Subtopic: DNA Double Helix |
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| Assertion (A): | DNA has two chains having antiparallel polarity. |
| Reason (R): | In one chain of DNA at one end has a free phosphate moiety 5' end of ribose sugar and at other end the ribose has a free 3' OH group. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A) |
| 2. | Both (A) and (R) are true and (R) is not the correct explanation of (A) |
| 3. | (A) is true but (R) is false. |
| 4. | (A) is false but (R) is true. |
Subtopic: DNA Double Helix |
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Which of the following is always true concerning the base composition of DNA?
| 1. | In each single strand, the number of adenine residues equals the number thymine residues. |
| 2. | In each single strand, the number of adenine residues equals the number of guanine residues. |
| 3. | In a molecule of double stranded DNA, the ratio of adenine residues to thymine residues equals the ratio of cytosine residues to guanine residues. |
| 4. | In a molecule of double stranded DNA, the number of adenine residues plus thymine residues equals the number of cytosine residues plus guanine residues. |
Subtopic: DNA Double Helix |
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Which of the following two statements can be correctly considered as the conclusions of the Hershey and Chase experiment?
| I: | The lack of 35S-labeled DNA remaining in the solution after the bacteriophages had been allowed to adsorb to the bacteria showed that the phage DNA was transferred into the bacterial cell. |
| II: | The presence of almost all the radioactive 32P in the solution showed that the protein coat that protects the DNA before adsorption stayed outside the cell. |
| 1. | Only I | 2. | Only II |
| 3. | Both I and II | 4. | Neither I nor II |
Subtopic: Search for Genetic Material |
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In the Meselson-Stahl experiment on DNA replication, after one round of replication in 14N medium following growth in 15N medium, what is the ratio of DNA with intermediate density to DNA with light density?
1. 2:0
2. 1:1
3. 3:1
4. 1:3
1. 2:0
2. 1:1
3. 3:1
4. 1:3
Subtopic: Search for Genetic Material |
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Why is a capsule advantageous to a bacterium?
| 1. | It protects the bacterium from desiccation |
| 2. | It provides means of locomotion |
| 3. | It allows the bacterium to "hide" from the host's immune system. |
| 4. | It allows the bacterium to attach to the surface |
Subtopic: Search for Genetic Material:I |
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Subtopic: DNA vs RNA as Genetic Material |
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‘‘It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material’’ (Watson and Crick, 1953). What will be true regarding he statement quoted?
1. Only I is correct
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect
| I: | The ‘specific pairing’ refers to complementary base pairing. |
| II: | The ‘possible copying mechanism’ refers to conservative mechanism of DNA replication. |
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect
Subtopic: DNA Replication |
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During DNA replication, the proofreading activity of DNA polymerase ensures high fidelity of the newly synthesized strand. This proofreading function is due to the:
1. 5' to 3' polymerase activity
2. 3' to 5' exonuclease activity
3. 5' to 3' exonuclease activity
4. Helicase activity
1. 5' to 3' polymerase activity
2. 3' to 5' exonuclease activity
3. 5' to 3' exonuclease activity
4. Helicase activity
Subtopic: DNA Replication |
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Consider the two statements:
| I. | In bacteria, translation initiation occurs as soon as the 5' end of an mRNA is synthesized, and translation and transcription are coupled. |
| II. | This is not possible in eukaryotes because transcription and translation are carried out in separate compartments of the cell |
| 1. | Both I and II are correct and II explains I |
| 2. | Both I and II are correct but II is not a correct explanation of I |
| 3. | I is correct and II is incorrect |
| 4. | I is incorrect and II is correct |
Subtopic: Transcription |
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