Match each item in Column I with one item in Column II and chose your answer from the codes given below.
Column I |
Column II |
I. RNAi II. Ribozyme III. PCR IV. Monoclonal antibodies |
1. Fire and Mello 2. Thomas Cech 3. Kyle Mullis 4. Millstein and Kohler |
Codes:
I | II | III | IV | |
1. | 1 | 2 | 3 | 4 |
2. | 2 | 1 | 4 | 3 |
3. | 2 | 1 | 3 | 4 |
4. | 1 | 2 | 4 | 3 |
Consider the following statements:
I: | RNAi takes place in all eukaryotic organisms as a method of cellular defense. |
II: | It involves the silencing of a specific mRNA due to complementary dsDNA molecules that prevent the translation of mRNA. |
III: | Fire and Mello got the Nobel Prize for the discovery of RNAi. |
Which of the above statements are true?
1. | I and II only | 2. | I and III only |
3. | II and III only | 4. | I, II, and III |
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RNAi is a mechanism to silence genes with the help of :
1. | ssRNA | 2. | dsRNA |
3. | ssDNA | 4. | dsDNA |
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A biological process in which RNA molecules inhibit gene expression or translation, by neutralizing targeted mRNA molecules is known as:
1. | Bioprospecting | 2. | Molecular pharming |
3. | RNA interference | 4. | Insertional mutagenesis |
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Fire and Mello shared noble prize for RNAi while working on:
1. | Arabidopsis thaliana | 2. | Drosophila melanogaster |
3. | Coenorhabditis elegans | 4. | Zea mays |
I: | involves silencing of a specific mRNA due to a complementary dsRNA molecule that binds to and prevents translation of the mRNA (silencing). |
II: | has been used to create transgenic tobacco plants resistant to nematode Meloidogyne incognita |
1. | Only I is correct | 2. | Only II is correct |
3. | Both I and II are correct | 4. | Both I and II are incorrect |