- 1(current)
Q. No.Choose the correct option regarding Retrovirus:
| 1. | An RNA virus that synthesises DNA during infection |
| 2. | A DNA virus that synthesises RNA during infection |
| 3. | A ssDNA virus |
| 4. | A dsRNA virus |
Subtopic: Gene Therapy | Molecular Diagnosis |
72%
Level 2: 60%+
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A direct target for gene therapy would include all the following cells except:
| 1. | erythrocytes | 2. | muscle fibers |
| 3. | hepatocytes | 4. | vascular endothelium |
Subtopic: Gene Therapy |
Level 3: 35%-60%
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The first recombinant therapeutic product approved for human use was:
| 1. | Humulin | 2. | hGH |
| 3. | Factor VIII clotting factor | 4. | Erythropoietin |
Subtopic: Gene Therapy | Molecular Diagnosis |
93%
Level 1: 80%+
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The first clinical gene therapy was done for the treatment of:
| 1. | AIDS |
| 2. | Cancer |
| 3. | Cystic fibrosis |
| 4. | SCID (Severe Combined Immuno Deficiency) resulting from deficiency of ADA |
Subtopic: Gene Therapy |
94%
Level 1: 80%+
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Electroporation is:
| 1. | the process of separating charged molecules through a gel maintained in an electric field |
| 2. | the process of combining foreign DNA to an electrically charged vector molecule |
| 3. | the process of introducing DNA into cells by the application of high-voltage pulses |
| 4. | the process of protoplast fusion by the application of high-voltage pulses |
Subtopic: Gene Therapy |
50%
Level 3: 35%-60%
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Which of the following genetic disease would be amenable to genetic engineering?
| 1. | Down's syndrome | 2. | Muscular dystrophy |
| 3. | Cystic fibrosis | 4. | Cri du Chat |
Subtopic: Gene Therapy |
Level 3: 35%-60%
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α -1 antitrypsin is:
1. An antacid
2. An enzyme
3. Used to treat arthritis
4. Used to treat emphysema
1. An antacid
2. An enzyme
3. Used to treat arthritis
4. Used to treat emphysema
Subtopic: Gene Therapy | Vaccines |
90%
Level 1: 80%+
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Which of the following is one of the technical reasons why gene therapy is problematic?
| 1. | Most cells with an engineered gene do not produce gene products. |
| 2. | Most cells with engineered genes overwhelm other cells in a tissue. |
| 3. | Cells with transferred genes are unlikely to replicate. |
| 4. | Transferred genes may not have appropriately controlled activity. |
Subtopic: Gene Therapy |
Level 3: 35%-60%
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- 1(current)
Q. No.
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