Choose the correct option regarding Retrovirus:
1. | An RNA virus that synthesises DNA during infection |
2. | A DNA virus that synthesises RNA during infection |
3. | A ssDNA virus |
4. | A dsRNA virus |
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Match each item in Column I with one item in Column II and chose your answer from the codes given below.
Column I |
Column II |
I. RNAi II. Ribozyme III. PCR IV. Monoclonal antibodies |
1. Fire and Mello 2. Thomas Cech 3. Kyle Mullis 4. Millstein and Kohler |
Codes:
I | II | III | IV | |
1. | 1 | 2 | 3 | 4 |
2. | 2 | 1 | 4 | 3 |
3. | 2 | 1 | 3 | 4 |
4. | 1 | 2 | 4 | 3 |
Pathophysiology is the:
1. Study of physiology of pathogen
2. Study of normal physiology of the host
3. Study of altered physiology of the host
4. None of the above
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The first recombinant therapeutic product approved for human use was:
1. | Humulin | 2. | hGH |
3. | Factor VIII clotting factor | 4. | Erythropoietin |
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A fragment of nucleic acid (DNA or RNA) that can be used to identify, usually through autoradiography, specific DNA or RNA molecules bearing the complementary sequence is called:
1. | Vector | 2. | Probe |
3. | Selectable marker | 4. | Reporter gene |
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ELISA is based on the principle of:
1. Antibody opsonization
2. Antigen-antibody interaction
3. Radioactive immune assay
4. Creation of recombinant DNA
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A hybridization probe used in molecular diagnosis is commonly tagged with a radioactive isotope to allow for its visualization. A common such radioactive isotope that can be used is:
1. | 60Co | 2. | 32P |
3. | 15N | 4. | 131I |
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1. | Only I | 2. | Only II |
3. | Both I and II | 4. | Neither I nor II |