| 1. | transacetylase | 2. | the repressor of lac operon |
| 3. | permease | 4. | beta-galactosidase |
| A. | Histones are organized to form a unit of eight molecules called histone octamer. |
| B. | Histones are negatively charged basic proteins. |
| C. | Histones are rich in the basic amino acid residues - lysine and arginine. |
| D. | The positively charged DNA is wrapped around the histone octamer to form nucleosome. |
| E. | The packaging of chromatin at higher levels requires an additional set of proteins called non-histone chromosomal proteins. |
| 1. | A, B and D only | 2. | A, C and E only |
| 3. | C, D and E only | 4. | B, D and E only |
| A. | Isolation of DNA and its digestion by restriction endonucleases. |
| B. | Hybridisation using a labelled VNTR probe. |
| C. | Transferring of separated DNA fragments to synthetic membranes. |
| D. | Detection of hybridised DNA fragments by autoradiography. |
| E. | Separation of DNA fragments by electrophoresis. |
| 1. | A, E, C, B, D | 2. | A, E, B, C, D |
| 3. | A, B, D, C, E | 4. | A, D, B, E, C |
| A. | transcription unit in DNA is defined primarily by three regions : promoter, structural gene and terminator. |
| B. | The promoter is said to be located towards the 5'-end of the structural gene. |
| C. | The promoter is a DNA sequence that provides binding site for RNA polymerase. |
| D. | The promoter defines the template and coding strands. |
| E. | The terminator is located towards the 3'-end of the coding strand and it defines the end of the process of transcription. |
| 1. | A, B, C, D and E | 2. | B, C, D and E only |
| 3. | A, C, D and E only | 4. | A, B, C and D only |
| 1. | \(\rho\) (rho) | 2. | \(\gamma\) (gamma) |
| 3. | \(\alpha\) (alpha) | 4. | \(\sigma\) (sigma) |
| 1. | Jacque Monod | 2. | Franklin Stahl |
| 3. | George Gamow | 4. | Francis Crick |
| Statement I: | Transfer RNAs and ribosomal RNA do not interact with mRNA. |
| Statement II: | RNA interference (RNAi) takes place in all eukaryotic organisms as a method of cellular defence. |
| 1. | Statement I is correct but Statement II is incorrect |
| 2. | Statement I is incorrect but Statement II is correct |
| 3. | Both Statement I and Statement II are correct |
| 4. | Both Statement I and Statement II are incorrect |