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Q. No.With regard to insulin choose the incorrect statement(s).
a.
C-peptide is found attached with both A and B chains of insulin with the help of disulphide bonds.
b.
In 1983, both A and B chains were produced by introducing alien genes in plasmid of same E.coli by Eli Lilly.
c.
A-peptide and B-peptide of insulin are interconnected by peptide bonds in mature insulin.
d.
Insulin from an animal source may cause allergy or other types of reactions in some diabetic patients.
Choose the correct answer from the options given below.
1. (a) and (b) only
2. (c) and (d)
3. (a), (b) and (c)
4. (d) only
Subtopic: Â Med Applications & Humulin |
 58%
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| Assertion (A): | Insulin used for diabetes was earlier extracted from the pancreas of slaughtered cattle and pigs but now it is not used. |
| Reason (R): | Aarti along with some other patients took insulin injections in which insulin was from an animal source and they manifested an allergic response to that. |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
| 3. | (A) is True but (R) is False. |
| 4. | (A) is False but (R) is True. |
Subtopic: Â Med Applications & Humulin |
 81%
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| Assertion(A): | Functional ADA cDNA genes must be inserted in the lymphocytes at the early embryonic stage to treat SCID. |
| Reason(R): | Cells in the embryonic stage are mortal, differentiated and easy to manipulate. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true and (R) is not the correct explanation of (A). |
| 3. | (A) is true but (R) is false. |
| 4. | (A) is False but (R) is true. |
Subtopic: Â Gene Therapy |
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| Assertion(A): | We can grow meristem in vitro to get virus-free plants. |
| Reason(R): | Apical and lateral meristems are free of viruses. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true, but (R) is not the correct explanation of (A). |
| 3. | (A) is true, but (R) is false. |
| 4. | (A) is false, but (R) is true. |
Subtopic: Â Plant Tissue Culture |
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Assertion(A): Agrobacterium tumefaciens is popular in genetic engineering because this bacterium is associated with the roots of all cereal and pulse crops.
Reason(R): A gene incorporated in the bacterial chromosomal genome gets automatically transferred to the crop with which the bacterium is associated.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Reason(R): A gene incorporated in the bacterial chromosomal genome gets automatically transferred to the crop with which the bacterium is associated.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Subtopic: Â Intro to Agri Applications |
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Assertion(A): Agrobacterium tumifaciens is common pathogen of plant family poaceae.
Reason(R): Plants of poaceae family are highly sensitive to the bacteria Agrobacterium tumifaciens.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Reason(R): Plants of poaceae family are highly sensitive to the bacteria Agrobacterium tumifaciens.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Subtopic: Â Bt Crops |Â Interference RNA Tech |
 56%
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| Assertion(A): | Batch fermentation is said to be closed system. |
| Reason(R): | In batch fermentation, the conditions set up are not changed from outside one fermentation starts. |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
| 3. | (A) is True but (R) is False. |
| 4. | Both (A) and (R) are False. |
Subtopic: Â Med Applications & Humulin |
 71%
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| Assertion(A): | A gene from Bacillus thuringiensis is incorporated in plant genome to increase their yield. |
| Reason(R): | Bacillus thuringiensis has Bt toxin producing gene, which kills the larva of insects. |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
| 3. | (A) is True but (R) is False. |
| 4. | Both (A) and (R) are False. |
Subtopic: Â Intro to Agri Applications |Â Bt Crops |
 65%
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| Assertion(A): | Plant body is an antibody. |
| Reason(R): | It is an antibody produced by plants that have been genetically engineered with animal DNA. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A) |
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 3. | (A) is true but (R) is false. |
| 4. | Both (A) and (R) are false. |
Subtopic: Â Vaccines |Â Molecular Diagnosis |
 50%
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| Assertion(A): | The patenting of 'brazzein' by USA is a case of biopiracy. |
| Reason(R): | 'Brazzein' is actually a protein sweetener derived from West African plant - Pentadiplandra brazzeana and then its corresponding gene has been patented by USA. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 3. | (A) is true but (R) is false. |
| 4. | Both (A) and (R) are false. |
Subtopic: Â Ethical Issues |Â Biowar |
 82%
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