Q. No.The Adenosine deaminase deficiency results into:
1.
Digestive disorder
2.
Addison's disease
3.
Dysfunction of Immune system
4.
Parkinson's disease
For effective treatment of the disease, early diagnosis and understanding of its pathophysiology is very important. Which of the following molecular diagnostic techniques is very useful for early detection?
| 1. | ELISA Technique | 2. | Hybridization Technique |
| 3. | Western Blotting Technique | 4. | Southern Blotting Technique |
With regard to insulin, choose the correct options:
| a: | C-peptide is not present in mature insulin. |
| b: | The insulin produced by rDNA technology has C-peptide. |
| c: | The pro-insulin has C-peptide. |
| d: | A-peptide and B-peptide of insulin are interconnected by disulphide bridges. |
Choose the correct answer from the options given below:
| 1. | (a), (c) and (d) only | 2. | (a) and (d) Only |
| 3. | (b) and (d) only | 4. | (b) and (c) only |
Nowadays, it is possible to detect the mutated gene causing cancer by allowing the radioactive probe to hybridise its complementary DNA in clone of cells, followed by its detection using autoradiography because:
| 1. | mutated gene does not appear on a photographic film as the probe has no complementarity with it. |
| 2. | mutated gene does not appear on a photographic film as the probe has complementarity with it. |
| 3. | mutated gene partially appears on a photographic film. |
| 4. | mutated gene completely and clearly appears on a photographic film. |
When gene targeting involving gene amplification is attempted in an individual's tissue to treat disease, it is known as:
1. Molecular diagnosis
2. Safety testing
3. Biopiracy
4. Gene therapy
Which of the following is not an application of PCR (Polymerase Chain Reaction)?
1. Purification of isolated protein
2. Detection of gene mutation
3. Molecular diagnosis
4. Gene amplification
The laws and rules to prevent unauthorized exploitation of bio-resources are termed as:
1. Biopatenting
2. Bioethics
3. Bioengineering
4. Biopiracy
RNA interference is used for which of the following purposes in the field of biotechnology?
| 1. | to develop a plant tolerant to abiotic stresses |
| 2. | to develop a pest-resistant plant against infestation by nematode |
| 3. | to enhance the mineral usage by the plant |
| 4. | to reduce post-harvest losses |
ds RNA can be used during which one of the following ?
1. Gene sequencing
2. Polymerase Chain Reaction
3. Gene silencing
4. Autoradiography
| 1. | Genetically engineered lymphocytes are not immortal cells. |
| 2. | Retroviral vector is introduced into these lymphocytes. |
| 3. | Gene isolated from marrow cells producing ADA is introduced into cells at embryonic stages |
| 4. | Lymphocytes from patient's blood are grown in culture, outside the body. |
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