| 1. | Antigen binding site is located at C-terminal region of antibody molecules. |
| 2. | Constant region of heavy and light chains are located at C-terminus of antibody molecules. |
| 3. | Each antibody has two light and two heavy chain. |
| 4. | The heavy and light chains are held together by disulfide bonds. |
| Assertion (A): | Some human organs like liver, kidney fail to function normally and transplantation is the only remedy to enable the patient to live a normal life. |
| Reason (R): | Tissue matching and blood group matching are essential before undertaking any transplant and patient has to take immunosuppresant thereafter. |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A) |
| 2. | Both (A) and (R) are True but (R) is not the correct explanation of (A) |
| 3. | (A) is True but (R) is False. |
| 4. | (A) is False but (R) is True. |
| List-I | List-II | ||
| A. | Malignant tumors | I. | Destroy tumors |
| B. | MALT | II. | AIDS |
| C. | NACO | III. | Metastasis |
| D. | α - Interferons | IV. | Lymphoid tissue |
| 1. | A-III, B-IV, C-II, D-I | 2. | A-IV, B-III, C-II, D-I |
| 3. | A-III,B-IV ,C-I, D-II | 4. | A-III, B-I,C-IV ,D-II |
| List-I | List-II | ||
| A. | B-Lymphocytes | I. | Passive immunity |
| B. | Interferons | II. | Cell mediated immunity |
| C. | T-Lymphocytes | III. | Produce an army of proteins in response to pathogens |
| D. | Colostrum | IV. | Innate immunity |
| List-I | List-II | ||
| (A) | Cytokine barriers | (I) | Mucus coating of respiratory tract |
| (B) | Cellular barriers | (II) | Interferons |
| (C) | Physiological barriers | (III) | Neutrophils and Macrophages |
| (D) | Physical barriers | (IV) | Tears and Saliva |
| Options: | (A) | (B) | (C) | (D) |
| 1. | (II) | (III) | (IV) | (I) |
| 2. | (III) | (I) | (IV) | (II) |
| 3. | (III) | (I) | (II) | (IV) |
| 4. | (II) | (III) | (I) | (IV) |
| 1. | Acquired immunity is non-specific type of defense present at the time of birth. |
| 2. | Primary response is produced when our body encounters a pathogen for the first time. |
| 3. | Anamnestic response is elicited on subsequent encounters with the same pathogen. |
| 4. | Anamnestic response is due to memory of first encounter. |
Immuno-suppressants are administered to burn patients or during organ transplantation to suppress:
1. Innate immunity
2. Cytokine Storm
3. Humoral immunity
4. Cell-mediated immunity
| 1. | Inability of recipient to differentiate between 'self and 'non–self' tissues/cells |
| 2. | Humoral immune response only |
| 3. | Auto–immune response |
| 4. | Cell–mediated response |
| List-I | List-II | ||
| (a) | Cellular barrier | (i) | Interferons |
| (b) | Cytokine barrier | (ii) | Mucus |
| (c) | Physical barrier | (iii) | Neutrophils |
| (d) | Physiological barrier | (iv) | HCI in gastric juice |
| (a) | (b) | (c) | (d) | |
| 1. | (ii) | (iii) | (iv) | (i) |
| 2. | (ii) | (iii) | (i) | (iv) |
| 3. | (iii) | (iv) | (ii) | (i) |
| 4. | (iii) | (i) | (ii) | (iv) |
Identify the wrong statement with a reference to immunity.
| 1. | When ready-made antibodies are directly given, it is called “Passive immunity". |
| 2. | Active immunity is quick and gives a full response. |
| 3. | Foetus receives some antibodies from the mother, it is an example of passive immunity |
| 4. | When exposed to antigen(living or dead) antibodies are produced in the host's body. It is called "Active immunity |