In Lederberg's replica plating experiment, what shall be used to obtain streptomycin resistant strain?
1.  Minimal medium and streptomycin
2.  Complete medium and streptomycin
3.  Only minimal medium
4.  Only complete medium

Using imprints from a plate with a complete medium and carrying bacterial colonies, you can select streptomycin-resistant mutants and prove that such mutations do not originate as adaptation. These imprints need to be used:

1. On plates with and without streptomycin

2. Only on plates with streptomycin

3. On plates with minimal medium

4. Only on plates without streptomycin