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Q. No.Read the following statements carefully.
(i)
PCR is used to detect mutations in genes in suspected cancer patients.
(ii)
A direct method to insert a foreign gene into plant cells is micro-injection.
(iii)
The first transgenic cow, Rosie, produced human protein-enriched milk, i.e., 5.4 grams per litre.
(iv)
RNAi takes place in all eukaryotic organisms as a method of cellular defense.
How many of the above statements are correct?
1. 1
2. 2
3. 3
4. 4
Subtopic: Â Molecular Diagnosis |Â Transgenic Microbes & Animals |
 58%
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Match column I with column II and select the correct option.
1. a(ii), b(iv), c(i), d(iii)
2. a(i), b(ii), c(iii), d(iv)
3. a(iv), b(ii), c(i), d(iii)
4. a(ii), b(iv), c(iii), d(i)
| Column I | Column II | ||
| a. | Patent on Basmati rice by an American company | (i) | 1983 |
| b. | First clinical gene therapy | (ii) | 1997 |
| c. | Humulin by Eli Lilly Co. | (iii) | 1972 |
| d. | Construction of first recombinant DNA | (iv) | 1990 |
1. a(ii), b(iv), c(i), d(iii)
2. a(i), b(ii), c(iii), d(iv)
3. a(iv), b(ii), c(i), d(iii)
4. a(ii), b(iv), c(iii), d(i)
Subtopic: Â Ethical Issues |
 78%
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Read the following statements carefully.
| Statement A: | Increased agricultural yields have been partly due to the use of better management practices and use of agrochemicals, but mainly due to the use of improved crop varieties. |
| Statement B: | GMOs increased reliance on chemical pesticides by producing pesticide-resistant crops. |
| 1. | Both statements A and B are correct |
| 2. | Both statements A and B are incorrect |
| 3. | Statement A is correct, B is incorrect |
| 4. | Statement A is incorrect, B is correct |
Subtopic: Â Intro to Agri Applications |
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Assertion (A): In 1983, Eli Lilly used E.coli, as heterologous host for the production of humulin
Reason (R): Production of insulin in E.coli by genetic engineering is possible because bacterial cells can carry out the RNA splicing mechanism
Choose the correct answer from the options given below
1. Both (A) and (R) are true and (R) is the correct explanation of the (A)
2. Both (A) and (R) are true but (R) is not the correct explanation of the (A)
3. (A) is true but (R) us false
4. (A) is false but (R) is true
Reason (R): Production of insulin in E.coli by genetic engineering is possible because bacterial cells can carry out the RNA splicing mechanism
Choose the correct answer from the options given below
1. Both (A) and (R) are true and (R) is the correct explanation of the (A)
2. Both (A) and (R) are true but (R) is not the correct explanation of the (A)
3. (A) is true but (R) us false
4. (A) is false but (R) is true
Subtopic: Â Med Applications & Humulin |
 57%
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From the list of human diseases given below, which ones have transgenic models existing for them?
Select the correct option from the following
1. b and c only
2. a only
3. d and a only
4. a, b, c and d
| a. | Alzheimer's |
| b. | Rheumatoid arthritis |
| c. | Cystic fibrosis |
| d. | Cancer |
Select the correct option from the following
1. b and c only
2. a only
3. d and a only
4. a, b, c and d
Subtopic: Â Transgenic Microbes & Animals |
 85%
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With regard to insulin choose the incorrect statement(s).
Choose the correct answer from the options given below.
1. (a) and (b) only
2. (c) and (d)
3. (a), (b) and (c)
4. (d) only
| a. | C-peptide is found attached with both A and B chains of insulin with the help of disulphide bonds. |
| b. | In 1983, both A and B chains were produced by introducing alien genes in plasmid of same E.coli by Eli Lilly. |
| c. | A-peptide and B-peptide of insulin are interconnected by peptide bonds in mature insulin. |
| d. | Insulin from an animal source may cause allergy or other types of reactions in some diabetic patients. |
1. (a) and (b) only
2. (c) and (d)
3. (a), (b) and (c)
4. (d) only
Subtopic: Â Med Applications & Humulin |
 58%
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| Assertion (A): | Insulin used for diabetes was earlier extracted from the pancreas of slaughtered cattle and pigs but now it is not used. |
| Reason (R): | Aarti along with some other patients took insulin injections in which insulin was from an animal source and they manifested an allergic response to that. |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
| 3. | (A) is True but (R) is False. |
| 4. | (A) is False but (R) is True. |
Subtopic: Â Med Applications & Humulin |
 81%
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| Assertion(A): | Functional ADA cDNA genes must be inserted in the lymphocytes at the early embryonic stage to treat SCID. |
| Reason(R): | Cells in the embryonic stage are mortal, differentiated and easy to manipulate. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true and (R) is not the correct explanation of (A). |
| 3. | (A) is true but (R) is false. |
| 4. | (A) is False but (R) is true. |
Subtopic: Â Gene Therapy |
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| Assertion(A): | We can grow meristem in vitro to get virus-free plants. |
| Reason(R): | Apical and lateral meristems are free of viruses. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true, but (R) is not the correct explanation of (A). |
| 3. | (A) is true, but (R) is false. |
| 4. | (A) is false, but (R) is true. |
Subtopic: Â Plant Tissue Culture |
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Assertion(A): Agrobacterium tumefaciens is popular in genetic engineering because this bacterium is associated with the roots of all cereal and pulse crops.
Reason(R): A gene incorporated in the bacterial chromosomal genome gets automatically transferred to the crop with which the bacterium is associated.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Reason(R): A gene incorporated in the bacterial chromosomal genome gets automatically transferred to the crop with which the bacterium is associated.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Subtopic: Â Intro to Agri Applications |
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