Q. No.Whose experiments cracked the DNA and discovered unequivocally that a genetic code is a triplet?
1. Nirenberg and Matthaei
2. Hershey and Chase
3. Morgan and Sturtevant
4. Beadle and Tatum
1. Nirenberg and Matthaei
2. Hershey and Chase
3. Morgan and Sturtevant
4. Beadle and Tatum
Semiconservative replication of DNA was first demonstrated in:
1. Drosophila melanogaster
2. Escherichia coli
3. Streptococcus pneumoniae
4. Salmonella typhimurium
What is not true for genetic code?
| 1. | A codon in mRNA is read in non-contiguous fashion |
| 2. | It is nearly universal |
| 3. | It is degenerate |
| 4. | It is unambiguous |
| 1. | The total amount of purine nucleotides and pyrimidine nucleotides is not always equal |
| 2. | There are two strands, which run parallel in the 5' → 3’ direction |
| 3. | The proportion of adenine in relation to thymine varies with the organism |
| 4. | There are two strands, which run antiparallel - one in 5' → 3’ direction and the other in 3’→ 5’ |
1. GUU, GCU - Alanine
2. UAG, UGA - Stop
3. AUG, ACG - Start/methionine
4. UUA, UCA -Leucine
Telomere repetitive DNA sequences control the function of eukaryotic chromosomes because they:
1. act as replicons
2. are RNA transcription initiators
3. help chromosome pairing
4. prevent chromosome loss
Which one of the following pairs of nitrogenous bases of nucleic acids is wrongly matched with the category mentioned against it?
1. Thymine, Uracil - Pyrimidines
2. Uracil, Cytosine - Pyrimidines
3. Guanine, Adenine - Purines
4. Adenine, Thymine - Purines
Molecular basis of organ differentiation depends on the modulation in transcription by:
1. RNA polymerase
2. ribosome
3. transcription factor
4. anticodon
The length of the DNA molecule greatly exceeds the dimensions of the nucleus in eukaryotic cells. How is this DNA accommodated?
1. Deletion of non-essential genes
2. Super-coiling in nucleosomes
3. DNAse digestion
4. Through the elimination of repetitive DNA
During transcription, RNA polymerase holoenzyme binds to a gene promoter and assumes a saddle-like structure. What is its DNA-binding sequence?
| 1. | TIAA |
| 2. | AATI |
| 3. | CACC |
| 4. | TATA |
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