A sequence of pictures of polypeptide synthesis shows a ribosome holding two transfer RNAs. One tRNA has a polypeptide chain attached to it; the other tRNA has a single amino acid attached to it. What does the next picture show?
(a) The polypeptide chain moves over and bonds to the single amino acid
(b) The tRNA with the amino acid leaves the ribosome
(c) The amino acid moves over and bonds to the polypeptide chain
(d) The tRNA with the polypeptide chain leaves the ribosome

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Column-I                                               Column-II
I. Genome of ϕ 174 bacteriophage           (A) Ribozyme, RNAase
II. Purine                                               (B) 5386 Nucleotides
III. Catalytic RNA                                   (C) Adenine and Guanine
IV. Any chemical change in DNA              (D) Mutation
The correct match is:
(a) I - D, II - B, III - A, IV - C                 (b) I - B, II - A, III - D, IV - C
(c) I - D, II - C, III - A, IV - B                 (d) I - B, II - C, III - A, IV - D

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Column-I                                        Column-II
I. Operator site                               (A) Binding site for RNA polymerase
II. Promoter site                             (B) Binding site for repressor molecule
III. Structural gene                         (C) Codes for enzyme protein
IV. Regulator gene                          (D) Code for repressor molecules
The correct match is:
(a) I - B, II - A, III - C, IV - D          (b) I - B, II - A, III - D, IV - C
(c) I - D, II - C, III - A, IV - B          (d) I - B, II - C, III - A, IV - D

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Column-I                           Column-II
I. Termination                    (A) Aminoacyl tRNA synthetase
II. Translation                    (B) Okazaki fragments
III. Transcription                (C) GTP dependent release factor
IV. DNA replication             (D) RNA polymerase
The correct match is:
(a) I - B, II - A, III - C, IV - D            (b) I - C, II - A, III - D, IV - B
(c) I - D, II - C, III - A, IV - B            (d) I - B, II - C, III - A, IV - D

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In chromosome, DNA is associated with:

A. Negatively charged proteins       B. Positively charged proteins

C. Neutral proteins                        D. NHC protein

(a) B, D                 (b) A, B, C, D         (c) B, C, D             (d) A, B, C

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Heterochromatin:

A. Is more densely packed      B. Is stains dark

C. Is transcriptionally active    D. Is transcriptionally inactive

(a) A, C                 (b) A, B, C, D         (c) B, C, D             (d) A, B, D

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In 1953 James Watson and F. Crick proposed Double Helix model of DNA and got Nobel Prize their model of DNA was based on:
A. X-ray diffraction of DNA produced by M. Wilkins and R. Franklin
B. Griffith’s experiment.
C. Hershey - Chase experiment
D. Chargaff’s rule of base equivalence (A + G / T + C = 1)
(a) A, D              (b) A, B, C, D            (c) B, C, D             (d) A, B, C

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In one polynucleotide chain of a DNA molecule the ratio of A + T / G + C is 0.3. What is the A + G / T + C ratio of the entire DNA molecule:

(a) 0.3                  (b) 0.6                  (c) 1.2                  (d) 1

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DNA polymerase:
A. Is the main enzyme for RNA synthesis
B. Is DNA dependent DNA polymerizing enzyme
C. Is highly efficient enzyme
D. Is catalyses reaction with high degree of accuracy
(a) C, D              (b) A, B, C, D                (c) B, C, D             (d) A, B, C

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The difference(s) between mRNA and tRNA is / are that:
A. mRNA has more elaborated 3-dimensional structure due to extensive base-pairing.
B. tRNA has more elaborated 3-dimensional structure due to extensive pairing.
C. tRNA is usually smaller than mRNA.
D. mRNA bears anticodon but tRNA has codons.
(a) A, C                   (b) A, B, C, D                 (c) B, C                    (d) A, B, C

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