Choose the correct statement(s):
(a) Km (Michaelis - Menten) constant is the substrate concentration at which the enzymatic reaction attains half of its maximum velocity (1/2 Vmax)
(b) At lower Km, higher the substrate affinity for enzyme
(c) Vmax is reached when all the active sites of an enzyme are saturated with substrate
(d) All are correct
All of the above statements with respect to Michaelis-Menten equation which explains the enzyme kinematics, are correct.