Ca+2 bind ________ in the skeletal muscles and leads to exposure of the binding site for ________ on the filament _______:

(a) Troponin, myosin, actin                 (b) Troponin, actin, relaxin

(c) Actin, myosin, troponin                 (d) Tropomysin, myosin, actin

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Following is the figure of actin (thin) filaments. Identify A, B and C:

(a) A - Tropomyosin, B - Troponin, C - F-actin

(b) A - Troponin, B - Myosin, C - Tropomyosin

(c) A - Troponin, B - Tropomyosin, C - Myosin

(d) A - Troponin, B - Tropomyosin, C - F-actin

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The above figure is related with myosin monomer (meromyosin). Identify A to C:

(a) A - head, B - cross arm, C - GTP binding sites

(b) A - head, B - cross arm, C - Ca+2 binding sites

(c) A - head, B - cross arm, C - ATP binding sites

(d) A - cross arm, B - head, C - ATP binding sites

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The action potential that triggers a muscle contraction travels deep within the muscle cell by means of:

(a) Sarcoplasmic reticulum                 (b) Transverse tubules

(c) Synapse                                       (d) Motor end plates

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ATP provides energy for muscle contraction by allowing for:

(a) An action potential formation in the muscle cell

(b) Cross-bridge attachment of myosin to actin

(c) Cross-bridge detachment of myosin from actin

(d) Release of Ca+2 from sarcoplasmic reticulum

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A motor unit is best described as:

(a) All the nerve fibres and muscle fibres in a single muscle bundle

(b) One muscle fibre and its single nerve fibre

(c) A single motor neuron and all the muscle fibres that it innervates

(d) It is the neuron which carries the message from muscle to CNS

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Electrical excitation in a muscle fibre most directly causes:

(a) Movement of tropomyosin

(b) Attachment of the cross bridges to actin

(c) Release of Ca+2 from sarcoplasmic reticulum

(d) Splitting of ATP

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The energy for muscle contraction is most directly obtained from:

(a) Phosphocreatine                           (b) ATP

(c) Anaerobic respiration                    (d) Aerobic respiration

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Put the following phrases in proper order to describe what occurs at the neuromuscular junction to trigger muscle contraction:
I. Receptor sites on sarcolemma.
II. Nerve impulse.
III. Release of Ca+2 from sarcoplasmic reticulum
IV. The neurotransmitter acetylcholine is released
V. Sarcomere shortern
VI. Synaptic cleft
VII. Spread of impulses over sarcolemma on T-tubules
(a) II, IV, I, VI, VII, III, V            (b) II, IV, VI, I, VII, III, V
(c) I, II, III, IV, V, VI, VII             (d) VII, VI, V, IV, III, II, I

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Go through the following diagram describing muscle contraction:

Now identify A to E:
(a) A - Cross bridge, B - Cross bridge formation, C - Breaking of cross bridge, D - Sliding (rotation), E - ATP
(b) A - Cross bridge, B - Cross bridge formation, C - Sliding / rotation, D - Breaking of cross bridge, E - ATP
(c) A - Cross bridge, B - Breaking of Cross bridge, C - sliding / rotation, D - Cross bridge formation, E - AMP
(d) A - Cross bridge, B - Cross bridge formation, C - Sliding / rotation, D - ADP, E - Breaking of cross bridge

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