The linkage that joins two adjacent nucleotides in RNA is

(a) phosphate ester                 (b) phosphodiester

(c) phosphate anhydride          (d) N-glycoside

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Phosphodiester bond is present in

(a) ATP                    (b) ADP

(c) cAMP                  (d) none of these

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Heating may cause denaturation of enzyme or protein mainly by damaging its

(a) physical configuration

(b) chemical structure

(c) both physical configuration as well as chemical structure

(d) other properties.

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Which of the following is incorrect?

(a) The hair protein, keratin, is synthesized from the amino acid methionine

(b) Phospholipids act as carriers of small non polar molecules across the cell membrane

(c) Dietary intake of PUFA decreases the serum cholesterol level in our body

(d) Cobalt is a constituent of Vit B12

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Which of the following vitamins is a coenzyme for amino acid and fatty acid metabolism?

(a) Vitamin B6                (b) Vitamin B12

(c) Vitamin B1                (d) Vitamin B2

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The inhibition of succinic dehydrogenase by malonate is an example of

(a) competitive inhibition

(b) non-competitive inhibition

(c) allosteric modulation

(d) none of the above

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In RNA thymine is replaced by

(a) uracil                           (b) adenine

(c) thiamine                       (d) guanine

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An example of the competitive inhibition of an enzyme is the inhibition of:

(a) succinic dehydrogenase by malonic acid

(b) cytochrome oxidase by cyanide

(c) hexokinase by glucose -6-phosphate

(d) carbonic anhydrase by carbondioxide

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In which one of the following sets of three items each belong to the category mentioned against them?

(a) Lysine, glycine, thiamine - amino acids

(b) Myosin, oxytocin and gastrin -hormones

(c) Rennin, helicase and hyaluronidase - enzymes

(d) Optic nerve, oculomotor, vagus - sensory nerves

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The figure given below shows three velocity substrate concentration curves for an enzyme reaction. What do the curves a, b,  and c depict respectively?

(a) a - normal enzyme reaction

     b - competitive inhibition

     c - non-competitive inhibition

(b) a - enzyme with an allosteric modulator added

     b - normal enzyme activity

     c - competitive inhibition

(c) a - enzyme with an allosteric stimulator

     b - competitive inhibition added

     c - normal enzyme reaction

(d) a - normal enzyme reaction

     b - non-competitive inhibitor added

     c - allosteric inhibitor added

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