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Q. No.In polygenic inheritance:
1. traits have distinct alternate forms.
2. the expression of the genes is immune to the effects of the environment.
3. the phenotype reflects the contribution of each allele.
4. a single gene can exhibit multiple phenotypic expression.
Subtopic: Polygenic Inheritance & Pleiotropy |
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Identify the incorrect statement regarding mechanism of sex determination in varied organisms:
1. Male honeybees do not have a father and cannot have sons, but have a grandfather and can have grandsons.
2. Male grasshoppers have odd number of chromosomes in their somatic cells while the female grasshoppers have even number.
3. The females are heterogametic in birds.
4. If a couple has a daughter, they will have a son in next pregnancy as there is 50 percent probability of either a male or a female child in each pregnancy.
1. Male honeybees do not have a father and cannot have sons, but have a grandfather and can have grandsons.
2. Male grasshoppers have odd number of chromosomes in their somatic cells while the female grasshoppers have even number.
3. The females are heterogametic in birds.
4. If a couple has a daughter, they will have a son in next pregnancy as there is 50 percent probability of either a male or a female child in each pregnancy.
Subtopic: Sex Determination |
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Level 3: 35%-60%
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Which of the following are correct differences between sickle cell anaemia and thalassemia?
1. Only I and II
2. Only I
3. I, II and III
4. Only III
| Sickle Cell Anaemia | Thalassemia | ||
| I | Mode of inheritance | Autosomal recessive | Sex linked recessive |
| II | Cause | Substitution of valine by glutamic acid due to a single base substitution at the sixth codon of the beta globin chain | Mutation or deletion of genes located on chromosomes 11 or 16 |
| III | Effect on haemoglobin | Qualitative – incorrectly functioning globin | Quantitative – synthesis of too few haemoglobin molecules |
1. Only I and II
2. Only I
3. I, II and III
4. Only III
Subtopic: Mendelian Disorders: Sickle Cell Anemia | Mendelian Disorders | Mendelian Disorders: Thalassemia |
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Failure of segregation of chromatids during cell division cycle results in anuploidy. Given below are some important aneuploidies seen in humans. Identify the ones which are correctly matched to their description:
1. Only II and III
2. Only I
3. I, II and III
4. Only II
| I. | Down’s syndrome | Trisomy 21; Simian palmar crease, Furrowed tongue, Mental retardation |
| II. | Klinefelter’s syndrome | 47,XXY; Genetically female, gynaecomastia and sterility |
| III. | Turner’s syndrome | 45, XO; genetically male, Rudimentary ovaries, lack of secondary sexual characters |
2. Only I
3. I, II and III
4. Only II
Subtopic: Non - Disjunction & Aneuploidy | Sex Aneuploidy - Turner & Klinefelter Syndrome |
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The phenomenon of pleiotropism refers to:
| 1. | more than two genes affecting a single character. |
| 2. | presence of several alleles of a single gene controlling a single crossover. |
| 3. | presence of two alleles, each of the two genes controlling a single trait. |
| 4. | a single gene affecting multiple phenotypic expressions. |
Subtopic: Polygenic Inheritance & Pleiotropy |
80%
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Frequency of recombination between gene pairs on same chromosome as a measure of the distance between genes to map their position on chromosome, was used for the first time by:
| 1. | Henking | 2. | Thomas Hunt Morgan |
| 3. | Sutton and Boveri | 4. | Alfred Sturtevant |
Subtopic: Understanding Linkage | Linkage Types | Recombination & Gene Mapping |
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Which of the following statements are correct about Klinefelter's Syndrome?
Choose the correct answer from the options given below:
| A. | This disorder was first described by Langdon Down (1866). |
| B. | Such an individual has overall masculine development. However, the feminine development is also expressed. |
| C. | The affected individual is short statured. |
| D. | Physical, psychomotor and mental development is retarded. |
| E. | Such individuals are sterile. |
| 1. | A and E only | 2. | A and B only |
| 3. | C and D only | 4. | B and E only |
Subtopic: Non - Disjunction & Aneuploidy | Sex Aneuploidy - Turner & Klinefelter Syndrome |
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Broad palm with single palm crease is visible in a person suffering from-
| 1. | Thalassemia | 2. | Down's syndrome |
| 3. | Turner's syndrome | 4. | Klinefelter's syndrome |
Subtopic: Non - Disjunction & Aneuploidy | Sex Aneuploidy - Turner & Klinefelter Syndrome |
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Which one of the following symbols represents mating between relatives in human pedigree analysis?
| 1. | .svg) |
2. | .svg) |
| 3. | .svg) |
4. | .svg) |
Subtopic: Pedigree Analysis: Basics |
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Match List - I with List - II
Choose the correct answer from the options given below:
| List - I | List - II | ||
| (Type of cross) | (Phenotypic ratio) | ||
| (A) | Monohybrid cross | (I) | 1:1 |
| (B) | Dihybrid cross | (II) | 1:2:1 |
| (C) | Incomplete dominance | (III) | 3:1 |
| (D) | Test cross | (IV) | 9:3:3:1 |
| Options: | (A) | (B) | (C) | (D) |
| 1. | III | IV | II | I |
| 2. | II | IV | III | I |
| 3. | II | III | IV | I |
| 4. | IV | III | I | II |
Subtopic: Monohybrid Cross: Further Understanding | Dihybrid Cross: General Consideration | Dihybrid Cross: Details | Dominance Deviation from Mendel: 1 | Dominance Deviation from Mendel: 2 |
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