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Q. No.The main challenge for the production of insulin using rDNA techniques was:
1.
culturing bacteria containing recombinant DNA in labs
2.
finding suitable restriction enzymes to cut human DNA
3.
isolation of DNA in pure form from a human cell
4.
getting insulin assembled into a mature form
Subtopic: Med Applications & Humulin |
86%
Level 1: 80%+
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The first clinical gene therapy was given in 1990 to a 4-year-old girl with:
| 1. | adenosine deaminase (ADA) deficiency |
| 2. | alpha-1-antitrypsin deficiency |
| 3. | phenylalanine hydroxylase deficiency |
| 4. | homogentisic acid oxidase deficiency |
Subtopic: Gene Therapy |
96%
Level 1: 80%+
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ELISA stands for:
| 1. | Easily Located Immuno Specific Antigen |
| 2. | Early Live Inactive Surface Antigen |
| 3. | Energy Loaded Intermediate Site on Apoenzyme |
| 4. | Enzyme-Linked Immuno Sorbent Assay |
Subtopic: Molecular Diagnosis |
96%
Level 1: 80%+
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Root knot disease in tobacco is caused by:
1. Infective double stranded RNA
2. Abnormally folded proteins
3. Nematode Meloidogyne incognita
4. Nematode Caenorhabditis elegans
1. Infective double stranded RNA
2. Abnormally folded proteins
3. Nematode Meloidogyne incognita
4. Nematode Caenorhabditis elegans
Subtopic: Interference RNA Tech |
95%
Level 1: 80%+
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Creation of new varieties of pest-resistant GM crops:
| 1. | makes crops more resistant to abiotic stresses |
| 2. | reduces reliance on chemical pesticides |
| 3. | enhances nutritional value of food crops |
| 4. | increases efficiency of mineral usage by plants |
Subtopic: Intro to Agri Applications | Other GM Crops |
69%
Level 2: 60%+
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What was used to deliver the normal copy of gene in the gene therapy trials for ADA deficiency?
1. Microinjection
2. Biolistics
3. Retrovirus
4. Liposomes
1. Microinjection
2. Biolistics
3. Retrovirus
4. Liposomes
Subtopic: Gene Therapy |
86%
Level 1: 80%+
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Which one of the following techniques does not serve the purpose of early diagnosis of a disease for its early treatment?
| 1. | Enzyme Linked Immuno-Sorbent Assay (ELISA) technique |
| 2. | Recombinant DNA Technology |
| 3. | Serum and Urine analysis |
| 4. | Polymerase Chain Reaction (PCR) technique |
Subtopic: Molecular Diagnosis |
80%
Level 1: 80%+
NEET - 2023
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Select incorrect statement, regarding chemical structure of insulin:
| 1. | Mature insulin molecule consists of three polypeptide chains - A, B and C. |
| 2. | Insulin is synthesized as prohormone which contains extra stretch of C-peptide. |
| 3. | C-peptide is not present in mature insulin molecule. |
| 4. | Polypeptide chains A and B are linked to disulphide bridges. |
Subtopic: Med Applications & Humulin |
87%
Level 1: 80%+
NEET - 2023
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Match List - I with List - II
Choose the correct answer from the options given below:
| List-I | List-II | ||
| (A) | Gene therapy | (I) | Separation of DNA fragments |
| (B) | RNA interference | (II) | Diagnostic test for AIDS |
| (C) | ELISA | (III) | Cellular defense |
| (D) | Gel Electrophoresis | (IV) | Allows correction of a gene defect |
Choose the correct answer from the options given below:
| Options: | (A) | (B) | (C) | (D) |
| 1. | IV | I | II | III |
| 2. | IV | II | III | I |
| 3. | IV | III | II | I |
| 4. | IV | III | I | II |
Subtopic: Interference RNA Tech | Med Applications & Humulin | Gene Therapy | Molecular Diagnosis |
91%
Level 1: 80%+
NEET - 2023
Hints
Consider the two statements:
| Statement I: | The proteins encoded by the genes cryIAc and cryIIAb control the corn borer. |
| Statement II: | The proteins encoded by the gene cryIAb control the cotton bollworms. |
| 1. | Statement I is correct; Statement II is correct |
| 2. | Statement I is incorrect; Statement II is correct |
| 3. | Statement I is correct; Statement II is incorrect |
| 4. | Statement I is incorrect; Statement II is incorrect |
Subtopic: Bt Crops |
76%
Level 2: 60%+
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