NEET Botany Molecular Basis of Inheritance Questions Solved

NEET - 2017

During DNA replication, Okazaki fragments are used to elongate

(1) The leading strand towards replication fork

(2) The lagging strand towards replication fork

(3) The leading strand away from replication fork

(2) The lagging strand away from replication fork

(4) Okazaki fragments are short segments of replicating DNA. These have 1000-2000 bp in prokaryotes and 100-200 bp in eukaryotes. These fragments are used to elongate the lagging strand away from the replication fork.

Concept Enhancer - During replication the leading strand away with polarity 3' → 5' forms its complementary strand continuously, because 3' end of the latter is always open for elongation. On the other hand replication in lagging strand with plarity 5' → 3' is discontinuous, becuase only a short segment of DNA can be built in 5' → 3' direction at a time. As a result of this, okazaki fragments are formed, which are later joined by DNA ligase.

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