Anaphase promoting complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur?

(1) Chromosomes will not condense

(2) Chromosomes will be fragmented

(3) Chomosomes will not segregate

(4) Recombinantion of chromosome arms will occur 

Subtopic:  Cell Division: Mitosis (Karyokinesis) |
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DNA replication in bacteria occurs

(1) during S-phase

(2) within nucleolus

(3) prior to fission 

(4) just before transcription 

Subtopic:  Intro to Cell Cycle & Interphase |
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Which of the following options gives the correct sequences of events during mitosis?
(1)Condensationnuclear membrane disassemblycrossing overSegregationtelophase

(2)Condensationnuclear membrance disassemblyarrangement at equatorcentromere divisionsegregationtelophase

(3) Condensationcrossing overnuclear membrance disassemblysegregationtelophase

(4) Condensationarrangement at equator centromere divisionsegregationtelophase

Subtopic:  Cell Division: Mitosis (Karyokinesis) |
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During cell growth, DNA synthesis takes place in

(1) S-phase                       

(2) G1-phase

(3) G2-phase                     

(4) M-phase 

Subtopic:  Intro to Cell Cycle & Interphase |
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When cell has stalled DNA replication fork, which checkpoint should be predominantly activated?

(1) G1/s

(2) G2/M

(3) M

(4) Both G2/M and M

Subtopic:  Intro to Cell Cycle & Interphase |
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Match the stage of meiosis in column I to their characteristic features in column II and select the correct option using the codes given below 
  Column l                                                 Column ll
A. pachytene                                1. pairing of homologous chromosomes

B. Metaphase-l                             2. Terminalisation of chaismata

C. Diakinesis                                3. Crossing-over takes place
  
D. Zygotene                                 4. Chromosomes align at equatorial plate 

The correct option:

      A      B        C        D 
(a)  3      4        2        1
(b)  1      4        2        3
(c)  2      4        3        1
(d)  4      3        2       1   

Subtopic:  Cell Cycle: Meiosis I |
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A cell at telophase stage is observed by a student in a plant brought from the field. He tells his teacher that his cell is not like other cells at telophase stage. There is no formation of cell plate and thus the cell is containing more number of chromosomes as compared to other dividing cells. This would result in

(1) polyploidy

(2) somaclonal variation

(3) polyteny

(4) aneuploidy

Subtopic:  Cell Division: Mitosis (Karyokinesis) |
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Which of the following is not a characteristic feature during mitosis in somatic cells
(1) Disappearance of nucleolus

(2) Chromosome movement

(3) Synapsis

(4) Spindle fibres

Subtopic:  Cell Cycle: Meiosis I |
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Spindle fibres attach on to 

(1) Kinetochore of the chromosome

(2) centromere of the chromosome

(3) Kinetosome of the chromosome

(4) telomere of the chormosome 

Subtopic:  Cell Division: Mitosis (Karyokinesis) |
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In meiosis crossing over is initiated at 

1. leptotene

2. Zygotene

3. diplotene

4. pachytene

Subtopic:  Cell Cycle: Meiosis I |
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