Select the correct statements with respect to pleiotropism 
(a) A gene is said to be pleiotropy if it affects more than one trait 
(b) Phenylketonuria is an example of pleiotropy
(c) A condition where one gene has several alleles is referred to as pleiotropism 
(d) A trait is said to be pleiotropic if several genes control it 
Choose the correct answer from the options given below: 
1. (a) and (b) only 
2. (a) and (d) only 
3. (a), (b) and (c) only 
4. (b) ,(c) and (d) only 

Subtopic:  Polygenic Inheritance & Pleiotropy |
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Given below are two statements: One is labelled as Assertion (A) and the other is labelled as Reason (R) 
Assertion(A): A father will never pass the gene for haemophilia to his sons 
Reason (R) : Haemophilia is sex-linked (X-linked recessive traits. 
In the light of the above statements, choose the correct answer from the options given below 
1. (A) is correct but R is not correct 
2. (A) is not correct but (R) is correct 
3. Both (A) and (R) are correct (R) is the correct explanation of (A) 
4. Both (A) and (R) are correct but (R) is not the  correct explanation of (A) 

Subtopic:  Mendelian Disorders: Hemophilia |
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Match List-I with List-II

List-I List-II
(a) Haemophilia (i) Inborn error of metabolism which lacks an enzyme that converts phenylalanine into tyrosine
(b) Down's Syndrome (ii) Sex-linked recessive disorder defect in blood coagulation
(c)Phenylketonuria (iii) Presence of additional copy of X-chromosome  (44+XXY)
(d) Klinefelter's Syndrome (iv) Additional copy of chromosome number 21

Choose  the correct answer from the options given below:

(a) (b) (c) (d)
1. (ii) (iv) (i) (iii)
2. (iv) (ii) (i) (iii)
3. (ii) (iii) (i) (iv)
4 (i) (ii) (iii) (iv)
Subtopic:  Mendelian Disorders | Non - Disjunction & Aneuploidy | Sex Aneuploidy - Turner & Klinefelter Syndrome |
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Assuming that fur colour of an animal is dark, range of colour shade and white. A cross is made between a male (AABBCC) with dark fur colour and a female (aabbcc) with white fur colour. What would be the fur colour of F1 generation? 
1. All intermediate colour 
2. Range of colour shade 
3. All dark colour 
4. All white colour 

Subtopic:  Polygenic Inheritance & Pleiotropy |
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In Drosophila, the genes for color of body and color of eyes are situated on _______.
1. both the sex chromosomes
2. autosomes 
3. Y-chromosome 
4. X-chromosome 

Subtopic:  Linkage | Recombination Gene Mapping |
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A low frequency recombination indicates that the genes are: 
1. Located far apart from each other 
2. Located close to each other 
3. Not linked 
4. Present on different c

Subtopic:  Linkage | Recombination Gene Mapping |
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Thomas Hunt Morgan's choice of Drosophila melanogaster has been proving to be useful even today. Which of the following has/have continued to make it a most useful species?
I. its four pairs of chromosomes
II. a very large number of visible as well as biochemically mutant phenotypes
III. easy and inexpensive maintenance
IV. short generation time and large number of offspring
1. II and III only
2. I, II, and III only
3. II, III, and IV only
4. I, II, III, and IV
Subtopic:  Chromosomal Basis of Inheritance: Introduction |
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Which of the following statements is true for linkage?
1. The closer two genes are on a chromosome, the lower the probability that a crossover will occur between them.
2. The observed frequency of recombination of two genes that are far apart from each other has a maximum value of 100%.
3. All of the traits that Mendel studied–seed color, pod shape, flower color, and others–are due to genes linked on the same chromosome.
4. Linked genes are found on different chromosomes
Subtopic:  Understanding Linkage | Linkage Types |
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Mendel accounted for the observation that traits which had disappeared in the F1 generation reappeared in the F2 generation by proposing that
1. new mutations were frequently generated in the F2 progeny, "reinventing" traits that had been lost in the F1.
2. the mechanism controlling the appearance of traits was different between the F1 and the F2 plants.
3. traits can be dominant or recessive, and the recessive traits were obscured by the dominant ones in the F1.
4. the traits were lost in the F1 due to dominance of the parental traits.
Subtopic:  Monohybrid Cross: 1 | Monohybrid Cross: Further Understanding |
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In the following questions a statement of assertion (A) is followed by a statement of reason (R).
Assertion (A): Organisms lacking one complete chromosome are called monosomics.
Reason (R): Down’s syndrome is an example of monosomy.
  
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
  1. If both the assertion and the reason are true and the reason is a correct explanation of the assertion
  2. If both the assertion and reason are true but the reason is not a correct explanation of the assertion
  3. If the assertion is true but the reason is false
  4. If both the assertion and reason are false
Subtopic:  Non - Disjunction & Aneuploidy | Sex Aneuploidy - Turner & Klinefelter Syndrome |
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