In DNA replication, the Okazaki fragments on the lagging strand are joined together by:

1. DNA ligase

2. DNA polymerase

3. Primase

4. Helicase 

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The enzyme that catalyzes the peptide bonding in prokaryotes is located in the:

1. Leader region of the mRNA

2. Central part of tRNA

3. Smaller subunit of the ribosome

4. Larger subunit of the ribosome

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If a cell were treated with a chemical that blocked nucleic acid synthesis, which of the following processes would most likely be affected first?

1. DNA replication 

2. tRNA synthesis 

3. mRNA synthesis

4. Protein synthesis

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In general, bacterial genes are regulated at the time of:

1. Transcription

2. Post transcription

3. Translation

4. Post translation  

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The insertion or deletion of a base pair into the genetic code will cause a frame shift mutation unless the number of base pairs inserted or deleted is:

(1) One

(2) Two

(3) three

(4) Ten

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If there are 999 bases in an RNA that codes for a protein with 333 amino acids and the base at position 901 is deleted such that the length of teh RNA becomes 998 bases, how many codons will be altered?

(1) 1

(2) 11

(3) 33

(4) 333

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DNA fragments are

(1) positively charged

(2) negatively charged

(3) neutral

(4) either positively or negatively charged depending on their size

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During DNA replication, Okazaki fragments are used to elongate

(1) The leading strand towards replication fork

(2) The lagging strand towards replication fork

(3) The leading strand away from replication fork

(2) The lagging strand away from replication fork

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Spliceosomes are not found in cells of 

(1) plants

(2) fungi

(3) animals 

(4) bacteria

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The final proof for DNA as the genetic material come from the experiments of 

(1) Griffith

(2) Hershey and chase 

(3) Avery, Macleod and McCarty 

(4) Hargobind Khorana 

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