Identify the incorrectly matched pair :

(1)

 Humulin

First therapeutic rDNA product approved for human use

(2)

RNAi

Silencing of mRNA with the help of dsRNA

(3)

Rosie

Transgenic sheep producing alpha 1 antitrypsin

(4)

Golden rice

Vitamin A enriched rice variety

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RNAi is a mechanism to silence genes with the help of 

(1) ssRNA

(2) dsRNA

(3) ssDNA

(4) dsDNA

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To protect tobacco plants against Meloidegyne incognita using RNAi, nematode specific genes were introduced in the plant using:

1. Transposons

2. Retrotransposons

3. Virus with RNA genome 

4. Agrobacterium

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A permanent cure for ADA deficiency could be:

(1) Enzyme replacement therapy

(2) Bone marrow transplant

(3) Introduction of a functional ADA cDNA into lymphocytes

(4) Introduction of gene isolate from marrow cells producing ADA into early embryonic cells

 

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Polymerase Chain Reaction is not used in :

1. Confirming presence of a pathogen during early infection

2. Identifying the mutated genes in suspected cancer patients

3. Isolating the gene of interest from host DNA to be cloned by recombinant procedures

4. Detection of the presence of HIV in suspected AIDS patient

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If gene isolate from marrow cells producing ADA is introduced into cells at early embryonic stage, it could be a permanant cure of ADA deficiency because the early embryonic cells :

1. Are more differentiated than the later stage cells

2. Are constantly dividing and do not get differentiated 

3. Are easy to manipulate than the later stage cells

4. Are virtually immortal 

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To test the safety of polio vaccine, the organisms used are transgenic :

1. Mice

2. Pigs

3. Monkey 

4. Cattle

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The first human hormone produced by recombinant technology was :

(1) Estrogen

(2) Growth hormone

(3) Erythropoietin

(4) Insulin

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If the goal were to create a plant resistant to an insecticide, which cell-based plant technology would be most effective ?

(1) clonal propagation

(2) cybridization

(3) protoplast fusion

(4) mutant selection

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Which protein has been produced generating a transgenic sheep that is used for replacement therapy for individuals at risk from emphysema?

(1) Plasminogen activator (rPA)

(2) α-antitrypsin (ATT)

(3) Casein

(4) Amyloid precursor proteins

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