Match List I with List II: 
List I List II
A.  \(\alpha-1\) antitrypsin  I.  Cotton bollworm
B.  Cry IAb II.  ADA deficiency
C.  Cry IAc III.  Emphysema
D.  Enzyme replacement therapy IV.  Corn borer
Choose the correct answer from the options given below:
1. A-III, B-I, C-II, D-IV
2. A-III, B-IV, C-I, D-II
3. A-II, B-IV, C-I, D-III
4. A-II, B-I, C-IV, D-III
Subtopic:  Intro to Agri Applications | Bt Crops | Gene Therapy |
 83%
From NCERT
NEET - 2024
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Match List - I with List - II
List-I List-II
(A) Gene therapy (I) Separation of DNA fragments
(B) RNA interference (II) Diagnostic test for AIDS
(C) ELISA (III) Cellular defense
(D) Gel Electrophoresis (IV) Allows correction of a gene defect

Choose the correct answer from the options given below:
Options: (A) (B) (C) (D)
1. IV I II III
2. IV II III I
3. IV III II I
4. IV III I II
Subtopic:  Interference RNA Tech | Med Applications & Humulin | Gene Therapy | Molecular Diagnosis |
 91%
From NCERT
NEET - 2023
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The genetic defect-Adenosine Deaminase (ADA) deficiency may be cured permanently by:

1. periodic infusion of genetically engineered lymphocytes having functional ADA cDNA
2. administering adenosine deaminase activators
3. introducing bone marrow cells producing ADA into cells at early embryonic stages
4. invitro cell culture therapy
Subtopic:  Gene Therapy |
 89%
From NCERT
AIPMT - 2009
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The site of production of ADA in the body is:

1. erythrocytes                               

2. lymphocytes                         

3. blood plasma                             

4. osteocytes

Subtopic:  Gene Therapy |
 87%
From NCERT
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The first clinical gene therapy was done for the treatment of

1. AIDS
2. Cancer
3. Cystic fibrosis
4. SCID (Severe Combined Immuno Deficiency resulting from the deficiency of ADA



 

Subtopic:  Gene Therapy |
 95%
From NCERT
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ADA is an enzyme which is deficient in a genetic disorder SCID. What is the full form of ADA?
1. Adenosine deoxyaminase     
2. Adenosine deaminase
3. Aspartate deaminase             
4. Arginine deaminase

Subtopic:  Gene Therapy |
 95%
From NCERT
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In gene therapy of Adenosine Deaminase (ADA) deficiency, the patient requires periodic infusion of genetically engineered lymphocytes because: 
1. Genetically engineered lymphocytes are not immortal cells.
2. Retroviral vector is introduced into these lymphocytes.
3. Gene isolated from marrow cells producing ADA is introduced into cells at embryonic stages 
4. Lymphocytes from patient's blood are grown in culture, outside the body.
Subtopic:  Gene Therapy |
 75%
From NCERT
NEET - 2022
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When gene targeting involving gene amplification is attempted in an individual's tissue to treat disease, it is known as:

1. Molecular diagnosis 2. Safety testing
3. Biopiracy 4. Gene therapy
Subtopic:  Gene Therapy |
 70%
From NCERT
NEET - 2021
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The Adenosine deaminase deficiency results into:

1. Digestive disorder  2. Addison's disease
3. Dysfunction of Immune system 4. Parkinson's disease
Subtopic:  Gene Therapy |
 83%
From NCERT
NEET - 2021
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Match the following columns and select the correct option.

Column-I Column-II
a. Bt cotton (i) Gene therapy
b. Adenosine deaminase deficiency (ii) Cellular defense
c. RNAi  (iii) Detection of HIV infection
d. PCR  (iv) Bacillus thuringiensis
 
a b c d
1. (iii) (ii) (i) (iv)
2. (ii) (iii) (iv) (i)
3. (i) (ii) (iii) (iv)
4. (iv) (i) (ii) (iii)

Subtopic:  Bt Crops | Interference RNA Tech | Gene Therapy | Molecular Diagnosis |
 94%
From NCERT
NEET - 2020
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