| List I | List II | ||
| A. | Down's syndrome | I. | \(11^{\text {th }}\) chromosome |
| B. | \(\alpha\) -Thalassemia | II. | \(' \mathrm{X} '\) chromosome |
| C. | \(\beta\) -Thalassemia | III. | \(21^{\text {st }}\) chromosome |
| D. | Klinefelter's syndrome |
IV. | \(16^{\text {th }}\) chromosome |
| Statement I: | Failure of segregation of chromatids during cell cycle, resulting in the gain or loss of whole set of chromosome in an organism, is known as aneuploidy. |
| Statement II: | Failure of cytokinesis after anaphase stage of cell division resulting in the gain or loss of chromosome is called polyploidy. |