Consider the following statements :
I. | RNAi takes place in all eukaryotic organisms as a method of cellular defence |
II. | It involves silencing of a specific mRNA due to complementary dsDNA molecules that prevents the translation of mRNA |
III. | Fire and Mello got Nobel Prize for the discovery of RNAi |
Which of the above statements are true ?
1. I and II only
2. I and III only
3. II and III only
4. I,II and III
A. | During open heart, surgery blood is circulated in the heart-lung machine. |
B. | Blockage in coronary arteries X-ray by angiography. |
C. | Computerized Axial Tomography (CAT) shows a detailed internal structure as seen in a section of the body. |
D | X-ray provides clear and detailed images of organs like prostate glands and lungs. |
1. B and D
2. C and D
3. A and C
4. A and B
Match the organism with its use in biotechnology.
(a) | Bacillus thuringiensis | (i) | Cloning vector |
(b) | Thermus aquaticus | (ii) | Construction of first rDNA molecule |
(c) | Agrobacterium tumefaciens | (iii) | DNA polymerase |
(d) | Salmonella typhimurium | (iv) | Cry proteins |
Select the correct option from the following:
(a) | (b) | (c) | (d) | |
1. | (iv) | (iii) | (i) | (ii) |
2. | (iii) | (ii) | (iv) | (i) |
3. | (iii) | (iv) | (i) | (ii) |
4. | (ii) | (iv) | (iii) | (i) |
Match the following columns and select the correct option.
Column-I | Column-II | ||
a. | Bt cotton | (i) | Gene therapy |
b. | Adenosine deaminase deficiency | (ii) | Cellular defense |
c. | RNAi | (iii) | Detection of HIV infection |
d. | PCR | (iv) | Bacillus thuringiensis |
a | b | c | d | |
1. | (iii) | (ii) | (i) | (iv) |
2. | (ii) | (iii) | (iv) | (i) |
3. | (i) | (ii) | (iii) | (iv) |
4. | (iv) | (i) | (ii) | (iii) |
With regard to insulin, choose the correct options:
(a) | C-peptide is not present in mature insulin. |
(b) | The insulin produced by rDNA technology has C-peptide. |
(c) | The pro-insulin has C-peptide. |
(d) | A-peptide and B-peptide of insulin are interconnected by disulphide bridges. |
1. | (a), (c) and (d) only | 2. | (a) and (d) Only |
3. | (b) and (d) only | 4. | (b) and (c) only |
Assertion (A): | Transgenic animals can be specifically designed to allow the study of how genes are regulated, and how they affect the normal functions of the body and its development, e.g., study of complex factors involved in growth such as insulin-like growth factor. |
Reason (R): | By introducing genes from other species that alter the formation of this factor and studying the biological effects that result, information is obtained about the biological role of the factor in the body. |
1. | Both (A) and (R) are True and (R) is the correct explanation of (A) |
2. | Both (A) and (R) are True but (R) is not the correct explanation of (A) |
3. | (A) is True but (R) is False |
4. | Both (A) and (R) are False |
1. | Golden rice | Vitamin B12 enriched rice |
2. | Rosie | First transgenic cow |
3. | Bt Cotton | Genetically modified pest resistant plant cotton variety |
4. | Basmati controversy | Biopiracy |
(a) | Pro-hormone insulin contain extra stretch of C-peptide |
(b) | A-peptide and B-peptide chains of insulin were produced separately in E.coli, extracted and combined by creating disulphide bond between them. |
(c) | Insulin used for treating Diabetes was extracted from Cattles and Pigs. |
(d) | Pro-hormone Insulin needs to be processed for converting into a mature and functional hormone. |
(e) | Some patients develop allergic reactions to the foreign insulin. |
Give below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).
Assertion (A): | In human beings, insulin is synthesized as a pro-hormone which needs to be processed before it becomes fully mature and functional. |
Reason (R): | The extra stretch of C-peptide is to be removed from A and B peptide chain of insulin. |
In the light of the above statements, Choose the most appropriate answer from the option given below :
1. | (A) is True but (R) is False. |
2. | (A) is False but (R) is True. |
3. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
4. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
Given below are two statements: one is labeled as Assertion (A) and the other is labeled as Reason (R).
Assertion (A): | The nematode cannot survive in a transgenic host which expresses specific interfering RNA. |
Reason (R): | Nematode-specific gene introduced in the host produces both sense and antisense complementary RNA which initiate RNA interference in the host cell. |
In light of the above statement, choose the most appropriate answer from the option given below :
1. | (A) is correct but (R) is not correct. |
2. | (A) is not correct but (R) is correct. |
3. | Both (A) and (R) are correct and (R) is the correct explanation of (A). |
4. | Both (A) and (R) are correct but (R) is not the correct explanation of (A). |