- 1(current)
Q. No.The adjoining graph shows change in conc. of substrate on enzyme activity. Identify A, B and C:
|
A |
B |
C |
|
|
1. |
Ki |
Km |
Vmax |
|
2. |
Km |
Ki |
|
|
3. |
Vmax |
Km |
|
|
4. |
Km |
Vmax |
Select the option which is not correct with respect to enzyme action.
| 1. | Substrate binds with enzyme as its active site |
| 2. | Addition of lot of succinate does not reverse the inhibition of succinic dehydogenase by malonate. |
| 3. | A non-competitive inhibitor binds the enzyme at a site distinct from that which binds the substrate |
| 4. | Malonate is a competitive inhibitor of succinic dehydrogenase |
Given below is the graph showing the effect of substrate concentration on enzyme activity. In the presence of a competitive inhibitor, when the concentration of the substrate is progressively increased:
| 1. | The Km value increases but the reaction will not achieve Vmax |
| 2. | The Km value increases but the reaction can ultimately achieve Vmax |
| 3. | The Km value decreases but the reaction will not achieve Vmax |
| 4. | The Km value decreases but the reaction can ultimately achieve Vmax |
The inhibition of succinic dehydrogenase by malonate is an example of
1. competitive inhibition
2. non-competitive inhibition
3. allosteric modulation
4. none of the above
In competitive inhibition:
| 1. | Inhibitor resembles the substrate in molecular structure |
| 2. | Competition between substrates and inhibitors to occupy active sites |
| 3. | Binding the inhibitors to active sites declines the enzyme action |
| 4. | All are correct |
The competitive inhibitor of enzyme succinic dehydrogenase is
1. succinate
2. malonate
3. malate
4. mannose
| 1. | Dinitrogenase | 2. | Succinic dehydrogenase |
| 3. | Amylase | 4. | Lipase |
| Statement I: | Low temperature preserves the enzyme in a temporarily inactive state whereas high temperature destroys enzymatic activity because proteins are denatured by heat. |
| Statement II: | When the inhibitor closely resembles the substrate in its molecular structure and inhibits the activity of the enzyme, it is known as competitive inhibitor. |
1. Statement I is false but Statement II is true.
2. Both Statement I and Statement II are true.
3. Both Statement I and Statement II are false.
4. Statement I is true but Statement II is false.
| 1. | Feedback inhibition |
| 2. | Competitive inhibition |
| 3. | Enzyme activation |
| 4. | Cofactor inhibition |
Which of the following set of coenzymes are nucleotides of vitamin niacin ?
| 1. | NAD, NADP | 2. | FMN, FAD |
| 3. | ATP, ADP | 4. | ATP, FAD |
- 1(current)
Q. No.
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