The figure given below shows the conversions of a substrate into product by an enzyme. In which one of the four options (1-4), the components of the reaction labelled as A, B, C and D are identified correctly:
Options
| A | B | C | D | |
| 1. | Transition state |
Potential energy |
Activation energy without enzyme |
Activation energy with enzyme |
| 2. | Potential energy |
Transition state |
Activation energy with enzyme |
Activation energy without enzyme |
| 3. | Activation energy with enzyme |
Transition state |
Activation energy without enzyme |
Potential energy |
| 4. | Potential energy |
Transition state |
Activation energy without enzyme |
Activation energy with enzyme |
Which of the following statements regarding enzyme inhibition is correct:
| 1. | Competitive inhibition is seen when a substrate competes with an enzyme for binding to an inhibitor protein |
| 2. | Non-competitive inhibitors often bind to the enzyme irreversibly |
| 3. | Competitive inhibition is seen when the substrate and the inhibitor compete for the active site on the enzyme |
| 4. | Non-competitive inhibition of an enzyme can be overcome by adding large amounts of substrate |
The catalytic efficiency of two different enzymes can be compared by the:
| 1. | The Km value |
| 2. | The pH optimum value |
| 3. | Molecular size of the enzyme |
| 4. | Formation of the product |
Role of enzyme in reactions is to:
| 1. | Decrease activation energy | 2. | Increase activation energy |
| 3. | Act as an inorganic catalyst | 4. | None of the above |