Prosthetic groups differ from co-enzymes in that
1. they require metal ions for their activity.
2. they (prosthetic groups) are tightly bound to apoenzymes.
3. their association with apoenzymes is transient.
4. they can serve as co-factors in a number of enzyme-catalyzed reactions.

Consider the following statements:

Select the correct option

1. (A) is False but (B) is True

2. Both (A) and (B) are True

3. (A) is True but (B) is False

4. Both (A) and (B) are False