NEET Zoology Biotechnology Principles and Processes Questions Solved

BOARD

(i) Why was bacterium used in the first instance of the construction of an
     artificial recombinant DNA molecule?
(ii) Name the scientists who accomplished this and how?

(i) Salmonella typhimurium was used in the first instance of the
    construction of artificial recombinant DNA molecule because it
    has plasmid which has an autonomously replicating circular
    extrachromosomal DNA. It also has an antibiotic resistance gene.

(ii) Stanely Cohen and Herbert Boyer accomplished this in 1972.
     Antibiotic resistant gene was isolated using restriction enzyme and introduced into the plasmid         of  bacterium - Salmonella typhimurium.
     Later the recombinant plasmid was introduced into the bacterium - E.coli so that it could make         copies of gene.

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