First clinical gene therapy was given in 1990 to a 4 years old girl for

(1) adenine deficiency

(2) growth deficiency

(3) adenosine deaminase deficiency

(4) adenosine deficiency

RNA interference is essential for the

(1) cell proliferation

(2) cell defence

(3) cell differentiation

(4) micropropagation

Genetically modified (GM) crops can be produced by

(1) recombinant DNA technology

(2) somatic hybridization

(3) cross breeding

(4) micropropagation

Which of the following genes do not occur naturally in living organisms?

1. Bt genes
2. RNAi genes
3. Cry genes
4. Endogeneous cytoplasmic defense genes

Adenosine deaminase (ADA deficiency) could be permanently cure, if the gene isolated from marrow cells producing ADA is introduced into cell at

(1) early embryonic stages

(2) Late embryonic stages

(3) early childhood

(4) None of the above

The first clinical gene therapy was given for treating

(1) diabetes mellitus

(2) chickenpox

(3) rheumatoid arthritis

(4) adenosine deaminase deficiency

The source of taq polymerase used in PCR is a

(1) thermophilic fungus

(2) mesophilic fungus

(3) thermophilic bacterium

(4) halophilic bacterium

The protein products of the following Bt toxin genes cry I Ac and cry II Ab are responsible for controlling

(1) bollworm

(2) roundworm

(3) moth

(4) fruit fly

Three critical research areas of biotechnology are:

I. Providing the best catalyst in the form of improved organism usually a microbe or pure enzyme

II. Multiple Ovulation Transfer Technology (MOET)

III. Creating optimal conditions through engineering for a catalyst to act.

IV. Downstream processing technologies

(1) I, II, III, IV      

(2) I, III, IV          

(3) I, II                 

(4) II and IV

Bt toxin is: 

(1) Intracellular lipids                      

(2) Intracellular crystalline protein

(3) Extracellular crystalline protein    

(4) Intracellular polysaccharide