Statements related to human Insulin are given below.
Which statement(s) is/are correct about genetically engineered Insulin?
 
(a) Pro-hormone insulin contain extra stretch of C-peptide
(b) A-peptide and B-peptide chains of insulin were produced separately in E.coli, extracted and combined by creating disulphide bond between them.
(c) Insulin used for treating Diabetes was extracted from Cattles and Pigs.
(d) Pro-hormone Insulin needs to be processed for converting into a mature and functional hormone.
(e) Some patients develop allergic reactions to the foreign insulin.

Choose the most appropriate answer from the options given below:
1. (c), (d) and (e) only
2. (a), (b) and (d) only
3. (b) only
4. (c) and (d) only

Subtopic:  Med Applications & Humulin |
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Genetically engineered insulin for human is produced from:
1. Escherichia coli
2. Psuedomonas putida
3. Bacillus thuringiensis
4. Rhizobium meliloti

Subtopic:  Med Applications & Humulin |
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Give below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).

Assertion (A): In human beings, insulin is synthesized as a pro-hormone which needs to be processed before it becomes fully mature and functional.
Reason (R): The extra stretch of C-peptide is to be removed from A and B peptide chain of insulin.

 
In the light of the above statements, Choose the most appropriate answer from the option given below :

1. (A) is correct but (R) is not correct.
2. (A) is not correct but (R) is correct.
3. Both (A) and (R) are correct and (R) is the correct explanation of (A).
4. Both (A) and (R) are correct but (R) is not the correct explanation of (A).
Subtopic:  Med Applications & Humulin |
 78%
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Given below are two statements: one is labeled as Assertion (A) and the other is labeled as Reason (R).

Assertion (A):  The nematode cannot survive in a transgenic host which expresses specific interfering RNA.
Reason (R):  Nematode-specific gene introduced in the host produces both sense and antisense complementary RNA which initiate RNA interference in the host cell.


In light of the above statement, choose the most appropriate answer from the option given below :

1. (A) is correct but (R) is not correct.
2. (A) is not correct but (R) is correct.
3. Both (A) and (R) are correct and (R) is the correct explanation of (A).
4. Both (A) and (R) are correct but (R) is not the correct explanation of (A).
Subtopic:  Interference RNA Tech |
 83%
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Mark the incorrect match
1. Gene therapy – Use of retrovirus to introduce cDNA into the host cell.
2. PCR – Used to detect mutations is genes in suspected cancer patients
3. ELISA – Detection of non-proteinecious  antigens.
4. Probe – A single strand DNA or RNA, tagged with radioactive molecule, will never hybridized with mutated gene
 
Subtopic:  Molecular Diagnosis |
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A:  Agrobacterium tumefaciens is popular in genetic engineering because this bacterium is associated with roots of pulse crops.
R:  A gene incorporated in the bacterial chromosomal genome gets automatically transferred to the crop with which the bacterium is associated

In the following questions a statement of assertion (A) is followed by a statement of reason (R).
1.  If both Assertion & Reason are true and the reason is the correct explanation of the assertion, then mark (1)
2.  If both Assertion & Reason are true but the reason is not the correct explanation of the assertion, then mark (2)
3.  If Assertion is true statement but Reason is false, then mark (3)
4.  If both Assertion and Reason are false statements, then mark (4)
  1. If both the assertion and the reason are true and the reason is a correct explanation of the assertion
  2. If both the assertion and reason are true but the reason is not a correct explanation of the assertion
  3. If the assertion is true but the reason is false
  4. If both the assertion and reason are false
Subtopic:  Other GM Crops |
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Which of the following processes is involved to control parasite Meloidogyne incognita?
1. Process based on chemical control
2. Process based on RNA interference
3. Toxin coded by a gene CryIAc
4. Recombinant DNA-technology 
Subtopic:  Interference RNA Tech |
 89%
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First clinical gene therapy was given in 1990 to a 4-year old girl child for treating
1. Insulin dependent diabetes
2. Phenylketonuria
3. Cystic fibrosis
4. Adenosine deaminase deficiency
Subtopic:  Gene Therapy |
 96%
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Given below are two statements : 
Statement I: Proteins encoded by genes cryIAc and cryllAb control corn borer, that of crylAb control the cotton bollworms 
Statement II: Bt toxin protein exist as inactive protoxins but once an insect ingests the inactive toxin, it is converted into an active form of toxin due to the alkaline pH of the gut 
In light of the above statements, choose the most appropriate answer from the options given below:
1. Both Statement I and Statement II are true 
2. Both Statement I and Statement II are false 
3. Statement I is true and Statement II is false 
4. Statement I is false but Statement II is true 
Subtopic:  Bt Crops |
 77%
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Milk of transgenic 'Cow Rosie' was nutritionally more balanced product for human babies than natural cow milk because it contained:
1. Human protein \(\alpha\) –1–antitrypsin.
2. Human alpha–lactalbumin.
3. Human insulin–like growth factor.
4. Human enzyme Adenosine Deaminase (ADA).
Subtopic:  Transgenic Microbes & Animals |
 82%
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