Which one of the following pairs of hormones are the examples of those that can easily pass through the cell membrane of the target cell and bind to a receptor inside it (mostly in the nucleus)?
1. Insulin and glucagon
2. Thyroxin and insulin
3. Somatostatin and oxytocin
4. Cortisol and testosterone
Which one of the following pairs is incorrectly matched?
1. Glucagon - Beta cells (source)
2. Somatostatin - Delta cells (source)
3. Corpus luteum - Relaxin (secretion)
4. Insulin - Diabetes mellitus (disease)
The blood calcium level is lowered by the deficiency of ?
1. parathormone
2. thyroxine
3. calcitonin
4. Both 1. and 2.
The posterior pituitary gland is not a ‘true’ endocrine gland because
1. it is provided with a duct
2. it only stores and releases hormones
3. it is under the regulation of hypothalamus
4. it secretes enzymes
When kidney of a person is damaged, he/she invariably suffers from anaemia because
1. RBCs pass through the glomerulus
2. Sufficient erythropoietin is not produced
3. haemoglobin is not synthesized sufficiently
4. Iron and vitamin B-12 are not able to bind to haemoglobin
The hormone that acts on the exocrine pancreas and stimulates the secretion of water and bicarbonate ions is:
1. Gastrin
2. Secretin
3. Cholecystokinin
4. Gastric inhibitory peptide
A person with Addison disease ___________.
| 1. | is unable to replenish blood glucose levels under stressful conditions |
| 2. | develops dramatically more male features |
| 3. | develops a rounded face and edema |
| 4. | has overgrowth of hands and face |
The actions of adrenaline will include all the following except:
1. Piloerection
2. Pupilary dilation
3. Glycogenesis
4. Positive ionotropic and chronotropic effect on heart
What would not be true for pancreas?
| 1. | The exocrine pancreatic acini secrete digestive enzymes |
| 2. | The endocrine islets of Langerhans constitute about 50% of the gland |
| 3. | The hormones secreted by endocrine pancreas are peptides |
| 4. | Alpha cells secrete glucagon, beta cells secrete insulin and delta cells secrete somatostatin |
Which of the following option gives the correct categorization of hormones according to their chemical nature?
|
A Steroid |
B Amino-acid derivative |
C Iodothyromines |
|
|
1. |
Epinephrine, nor-epinephrine |
Estradiol, progesterone |
Thyroxine |
|
2. |
Estradiol, progesterone |
Epinephrine, nor-epinephrine |
Thyroxine |
|
3. |
Estradiol, epinephrine |
Nor-epinephrine progesterone |
Thyroxine |
|
4. |
Estradiaol, pogesterone |
Thyroxine |
Epinephrine, nor-epinephrine |
Which of the following is incorrect with respect to parathyroid hormone (PTH)?
1. Secretion of PTH is regulated by circulating levels of calcium ions.
2. PTH acts on bones and stimulates the process of bone mineralisation.
3. PTH stimulates the reabsorption of Ca+2 by renal tubules.
4. PTH increases the absorption of Ca+2 from digested food.
The given table enlists various hormones and their chemical nature.
Hormone Chemical composition
(1) ___(i)____ Peptide
(2) Testosterone ___(ii)____
(3) Thyroxine ___(iii)____
(4) ___(iv)____ Amino-acid derivative
Which is the correct option that completes the given table?
1. i-Cortisol; ii-Steroids; iii-Polypeptide; iv-Estradiol
2. i-Insulin; ii-Proteins; iii-Polypeptide, iv-Epinephrine
3. i-Cortical; ii-Proteins; iii-Iodothyronines; iv-Estradiol
4. i-Insulin; ii-Steroids; iii-Iodothyronines; iv-Epinephrine
An impairment affecting synthesis or release of ADH results in a diminished ability of the kidney to conserve water leading to water loss and dehydration. This hormone released in blood by which of the following labeled structure in the given diagram?
(1) A
(2) B
(3) C
(4) D&A
How many of these hormones will interact with the membrane-bound receptor/
Thyroxine, Epinephrine, Progesterone, Insulin Estrogen.
(1) Three
(2) Two
(3) Five
(4) One
Oxytocin and Vasopressin are :-
1. Synthesized by pars nervosa
2. Stored in hypothalamus
3. Synthesized and stored by hypothalamus
4. Stored and Stored and released by neurohypophysis
One of these pairs are not correctly matched
1. Insulin – Raised blood sugar
2. Cretinism – Mental retardation
3. Grave's Disease – swollen facial tissues
4. Parathyroid – Tetany
The Source of somatostatin is the same as that of:
(1) Insulin and glucagon
(2) Vasopressin and oxytocin
(3) Thyroxine and calcitonin
(4) Somatotropin and prolactin
Which of the following is caused by severe hypothyroidism in childhood?
1. Grave’s disease
2. cretinism
3. Hashimoto’s disease
4. myxedema
Select the incorrect statement about parathormone
(1) Hypercalcemic hormone
(2) Decrease in the level of Ca2+ ions in the blood plasma would stimulate the release of PTH
(3) Increases Ca2+ absorption from the digested food
(4) Excess of parathormone would cause parathyroid tetany
MSH is secreted by:
1. Anteria lobe of the pituitary
2. Middle lobe of the pituitary
3. Posterior lobe of the pituitary
4. Endostyle
| Assertion (A): | PTH is hypercalcemic hormone. |
| Reason (R): | It increases the blood glucose level. |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
| 3. | (A) is True but (R) is False. |
| 4. | Both (A) and (R) are False. |
| 1. | Thyroid gland secretes only iodothyronines |
| 2. | ADH and ANF are synergistic to each other |
| 3. | All hypothalamic hormones originate in the hypothalamic neurons, pass through axons and are released from their nerve endings in the pituitary gland |
| 4. | Gonads and pancreas do not only function as endocrine glands. |
| I: | plays a very important role in the regulation of a 24-hour (diurnal) rhythm of our body. |
| II: | influences metabolism, pigmentation, the menstrual cycle as well as our defense capability. |
| 1. | four parathyroid glands are present on the back side of the thyroid gland, one pair each in the two lobes of the thyroid gland. |
| 2. | four parathyroid glands are present on the front side of the thyroid gland, one pair each in the two lobes of the thyroid gland. |
| 3. | two parathyroid glands are present on the back side of the thyroid gland, one each in the two lobes of the thyroid gland. |
| 4. | two parathyroid glands are present on the front side of the thyroid gland, one each in the two lobes of the thyroid gland. |
| 1. | It is a composite gland which acts as both exocrine and endocrine gland. |
| 2. | The endocrine pancreas consists of ‘Islets of Langerhans’. |
| 3. | There are about 1 to 2 million Islets of Langerhans in a normal human pancreas representing 90 percent of the pancreatic tissue. |
| 4. | It is an organ of the digestive system and endocrine system of vertebrates. |
| I: | Gastrin acts on the gastric glands and inhibits the secretion of hydrochloric acid and pepsinogen. |
| II: | Secretin acts on the endocrine pancreas and inhibits secretion of water and bicarbonate ions. |
| III: | CCK acts on both pancreas and gall bladder and inhibits the secretion of pancreatic enzymes and bile juice, respectively. |
| IV: | GIP inhibits gastric secretion and motility. |
| 1. | 1 | 2. | 2 |
| 3. | 3 | 4. | 4 |
| 1. | Only I | 2. | Only II |
| 3. | Both I and II | 4. | Neither I nor II |