IgM:
1. | has five antigen-binding sites. |
2. | has the ability to cross the placenta. |
3. | attaches to mast cells and basophils. |
4. | has five constant regions. |
Opsonization :
1. | is the killing of target cells by cytotoxic T cells. |
2. | is the secretory component of IgA. |
3. | helps increase phagocytosis. |
4. | is the interaction that allows IgG to cross the placenta. |
The antigen-binding sites of an antibody molecule are formed from the molecule's variable regions. Why are these regions described as variable?
1. | They can change their shapes to fit different antigens. |
2. | They change their shapes when they bind to an antigen. |
3. | Their specific shapes are unimportant. |
4. | The amino acid sequences of these regions vary widely among antibodies from different B cells. |
The class of immunoglobulins that attach to mast cells and basophils to initiate an inflammatory response are:
1. | IgA | 2. | IgM |
3. | IgG | 4. | IgE |
The cells responsible for humoral adaptive immune responses proliferate and differentiate into plasma cells in the:
1. | liver | 2. | bloodstream |
3. | lymph nodes | 4. | red pulp of the spleen |
CD4 and CD8 proteins can be best described as:
1. | attachment proteins on the surfaces of helper-T and cytotoxic T-cells |
2. | different protein chains seen in IgG and IgM antibodies |
3. | proteins on microbes that identify them as foreign |
4. | the proteins that antigen-presenting cells display along with foreign antigens |
An antibody molecule has an antigen-binding site located in the:
1. | hinge region |
2. | disulfide bonds |
3. | constant region of the L chains |
4. | variable regions of the H and L chains |
An immune process where particles such as bacteria are targeted for destruction by an immune cell known as a phagocyte is called as:
1. | chemotaxis | 2. | opsonization |
3. | cloning | 4. | anergy |
Where do the T-lymphocytes develop the ability to recognize self from non-self antigens?
1. | plasma cells | 2. | spleen |
3. | thymus | 4. | liver |
Antibodies present in colostrum protects the newborn from certain diseases which are of:
1. | Ig G type | 2. | Ig A type |
3. | Ig D type | 4. | Ig E type |
Which of the following is not lymphoid tissue?
1. | Spleen | 2. | Tonsils |
3. | Pancreas | 4. | Thymus |
Anamnestic response in acquired immunity is due to the fact that it is:
1. | characterized by memory | 2. | pathogen specific |
3. | huge in magnitude | 4. | due to lymphocytes |
B cells:
1. | Do not produce antibodies but help T cells produce them |
2. | Are pathogen specific but do not retain the memory of previous encounters |
3. | Lack ability to distinguish between self and non-self |
4. | Are involved in humoral immune response |
Graft rejection is due to:
1. Innate immune response
2. Humoral immune response
3. Cell-mediated immune response
4. Auto-immune response
Secondary lymphoid organs:
1. | Are those where immature lymphocytes differentiate |
2. | Provide a site of interaction between lymphocytes and antigens |
3. | Are formed after birth |
4. | Are bone marrow and MALT |