RNAi is a mechanism to silence genes with the help of :
1. | ssRNA | 2. | dsRNA |
3. | ssDNA | 4. | dsDNA |
Fire and Mello shared noble prize for RNAi while working on:
1. | Arabidopsis thaliana | 2. | Drosophila melanogaster |
3. | Coenorhabditis elegans | 4. | Zea mays |
The two polypeptide chains of insulin protein are linked together by:
1. | disulfide bonds | 2. | hydrogen bonds |
3. | covalent bonds | 4. | ionic bonds |
What is the problem with providing a bone marrow transplant to a patient with SCID?
1. rejection of the graft by the recipient
2. graft-versus-host disease
3. cardiovascular failure
4. anaphylaxis
The viruses generally used for gene therapy are:
1. | ds DNA virus | 2. | ss DNA virus |
3. | Reovirus | 4. | Reterovirus |
Bacillus thuringiensis (Bt) strains have been used to design novel:
1. | Biofertilizers | 2. | Biometallurgic techniques |
3. | Biomineralization processes | 4. | Bioinsecticidal plants |
Widely used tool in the genetic engineering of crop plants involves:
1. | protoplast fusion | 2. | Agrobacterium mediation |
3. | transposon mediation | 4. | microinjection |
The sheep “Dolly” was cloned by using somatic cells from the donor’s:
1. | udder | 2. | skin |
3. | tongue | 4. | ear lobe |
Hargobind Khorana was awarded the noble prize for:
1. discovering DNA
2. discovering RNA
3. discovering DNA polymerase
4. chemical synthesis of a gene
Deficiency of human growth hormone was initially treated with growth hormone derived from:
1. | chemicals | 2. | mutant mice |
3. | human cadavers | 4. | pigs |
Clearing up oil spills has been possible due to the use of genetically engineered:
1. | E.coli | 2. | Agrobacterium |
3. | Saccharomyces | 4. | Pseudomonas |
Genetically engineered pest resistance has advantages over other forms of pest control. Identify the one which is not:
1. pesticides are expensive and time-consuming to apply
2. pesticides are rarely selective
3. pesticides accumulate in the environment
4. pesticides are ineffective now
Genetic engineering of nitrogen fixation is made difficult by the fact that it:
1. is complex process involving many enzymes
2. is a process that is partly anaerobic
3. involves about 15 genes (the Nif Genes)
4. All of these
Shelf life of tomato has been increased by genetic engineering. This tomato has been given the name:
1. Quorn
2. Flavr Savr
3. Pruteen
4. Free Martin
The first transgenic sheep to produce alpha 1 antitrypsin was :
1. | Rosie | 2. | Dolly |
3. | Tracy | 4. | Andy |
The use of transgenic animals, to produce relatively large quantities of rare proteins for use in medicine, is sometimes called:
1. | therapeutics | 2. | pharming |
3. | molecular treatment | 4. | biochemistry |
A piece of nucleic acid used to find a gene, by forming a hybrid with it, is called a :
1. probe
2. vector
3. restriction sequence
4.retrovirus
The first hormone produced by rDNA technology was:
1. estrogen
2. testosterone
3. thyroxin
4. insulin
Which of the following genetically modified product is used to dissolve blood clots in patients with coronary artery disease?
1. | streptokinase | 2. | urokinase |
3. | tPA | 4. | heparin |
A genetically engineered product used in the treatment of anaemia is:
1. | erythropoietin | 2. | hemopoietic |
3. | ferritin | 4. | transferrin |
The genetically engineered vaccine for prevention of hepatitis B is made with the help of the microbe:
1. E.coli
2. Agrobacterium
3. Saccharomyces
4. Psuedomonas
Which of the following are also called as “magical bullets”?
1. restriction enzymes
2. monoclonal antibodies
3. DNA ligases
4. plasmids
Interferons have been produced by rDNA technology. Interferons help to prevent and treat:
1. | bacterial infections | 2. | viral infections |
3. | rickettsial infections | 4. | protozoal infections |