Furrowed tongue and partially open mouth are characteristics of

(1) Edward’s syndrome

(2) Turner’s syndrome

(3) Down’s syndrome

(4) Klinefelter’s syndrome.

All are the characteristics of an individual from trisomy
of chromosome 21, except

1. Short stature

2. Gynaecomastia

3. Palm crease

4. Furrowed tongue

A cell at the telophase stage is observed by a student in a brought from the field. He tells his teacher that this cell is not like other cells at the telophase stage. There is no formation of a cell plate and thus the cell is containing more chromosomes as compared to other dividing cells. This would result in:

1. polyploidy

2. somaclonal variation

3. polyteny

4. aneuploidy

If a man consists of an extra copy of chromosome number 18, then the condition is known as

1. Monosomy

2. Trisomy

3. Nullisomy

4. Polyploidy

Myotonic dystrophy is

(1) Autosomal recessive trait

(2) Autosomal dominant trait

(3) X- linkeddominant trait

(4) X- linked recessive trait

Which of the following is not a feature of Down's Syndrome?

1. It is caused by a non-disjunction in an autosome

2. The affected individual has trisomy of chromosome 21

3. The aflected individual has a characteristic simian palmar crease

4. The mental development of affected individual is normal

Monosomy means:
1. Lack of one pair of chromosomes
2. Lack of one of any one pair of chromosome
3. Presence of an extra chromosome
4. Presence of an extra set of chromosomes

Aneuploidy results from :

1. Point mutations

2. Gross structural changes in chromosomes

3. Failure of cytokinesis after telophase stage of cell division

4. Failure of segregation of chromatids during cell division 

Down’s syndrome was first described in the year

(1) 1962

(2) 1866

(3) 1856

(4) 1863

A person with Down syndrome will show all the given
symptoms except

1. Many loops on finger tips.
2. Flat back of head
3. Big and wrinkled tongue
4. Narrow round face