In which of the following one may observe variation in DNA?

(1) Fragmentation

(2) Budding

(3) Amitosis

(4) mutation

Two phenotypically normal individuals have an affected child. What can we conclude about the parents?

1. they both carried the diesease allele

2. they are not the parents of the child

3. they are affected

4. no conclusions can be drawn

All the following are examples of Mendelian disorders except:

1.  Hemophilia

2.  Sickle cell anemia

3.  Phenylketonuria

4.  Down's syndrome

In Phenylketonuria,

1. Only I is correct
2. Only II is correct
3. Both are correct
4. Both are incorrect

Which one of the following traits are controlled by genes located on the differential part of X-chromosome?

1.  Porcupine skin and epidermolysis bullosa

2.  Beard in man and milk glands in female

3.  Color blindness and hemophilia

4.  Color blindness and cystic fibrosis

Which of the following is not a hereditary disease?

1. Haemophilia. 

2. Cretinism. 

3. Cystic fibrosis. 

4. Thalassemia.

Mendelian disorders are mainly determined by:
1. Alteration or mutation in a single gene.
2. Chromosomal gross structural changes.
3. Recombination between linked genes.
4. Jumping genes

In cases of Phenylketonuria:

1. The affected individual lacks an enzyme that converts the amino acid tyrosine into phenylalanine.

2. The affected individual makes an enzyme that converts the amino acid tyrosine into phenylalanine.

3. The affected individual makes an enzyme that converts the amino acid phenylalanine into tyrosine.

4. The affected individual lacks an enzyme that converts the amino acid phenylalanine into tyrosine.

How many diseases in the list given below are Mendelian disorders?

1.  Four

2.  Five

3.  Six

4.  Seven 

Match each item in Column I with one item in Column II and chose your answer from the codes given below:

1. I - v; II - vii; III - iii; IV - i

2. I - iv; II - vi; III - iii; IV - i

3. I - v; II - vi; III - iii; IV - ii

4. I - v; II - vi; III - iii; IV - i