Which parts of the nephron are involved in increasing medullary interstitial osmolarity in the human kidneys?
I: Ascending limb of loop of Henle
II: Distal convoluted tubule
1. Only I
2. Only II
3. Both I and II
4. Neither I nor II
Subtopic:  Concentration of Urine |
 62%
Level 2: 60%+
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Given below are two statements: 
Assertion (A): Vasa recta and Henle's loop play a significant role in maintaining high osmolarity of medullary interstitial fluid 
Reason (R): Osmolarity increases from 300 mOsmolL-1 to 1200 mOsmolL-1 as we move from cortex to medullary region 
 
1. Both (A) and (R) are True and (R) is the correct explanation of (A).
2. Both (A) and (R) are True but (R) is not the correct explanation of (A).
3. (A) is True but (R) is False.
4. Both (A) and (R) are False.
Subtopic:  Concentration of Urine |
 59%
Level 3: 35%-60%
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Which of the following is not important for maintaining the increasing osmolarity in the medullary interstitium?

1. The proximity between Henle's loop and vasa recta

2. Counter current flow in two limbs of tubule

3. The differential permeability of different segments of nephron

4. Counter current flow in two limbs of Vasa recta

Subtopic:  Concentration of Urine: II | Concentration of Urine |
Level 4: Below 35%
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Where, within the loop of Henle, do you expect that the fluid will be most concentrated?
1. In the ascending limb
2. In the descending limb
3. At the hairpin bend
4. Just when it is joining the distal convoluted tubule
Subtopic:  Nephron Part 1 | Nephron Part 2 | Concentration of Urine |
 55%
Level 3: 35%-60%
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