I: | Ascending limb of loop of Henle |
II: | Distal convoluted tubule |
Assertion (A): | Vasa recta and Henle's loop play a significant role in maintaining high osmolarity of medullary interstitial fluid |
Reason (R): | Osmolarity increases from 300 mOsmolL-1 to 1200 mOsmolL-1 as we move from cortex to medullary region |
1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
3. | (A) is True but (R) is False. |
4. | Both (A) and (R) are False. |
Which of the following is not important for maintaining the increasing osmolarity in the medullary interstitium?
1. The proximity between Henle's loop and vasa recta
2. Counter current flow in two limbs of tubule
3. The differential permeability of different segments of nephron
4. Counter current flow in two limbs of Vasa recta